×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Effect of CHEK2 missense variant I157T on the risk of breast cancer in carriers of other CHEK2 or BRCA1 mutations.
18930998
2009
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
Family history, genetic testing, and clinical risk prediction: pooled analysis of CHEK2 1100delC in 1,828 bilateral breast cancers and 7,030 controls.
19124502
2009
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Estrogen receptor status in CHEK2-positive breast cancers: implications for chemoprevention.
19021634
2009
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Identification of a novel CHEK2 variant and assessment of its contribution to the risk of breast cancer in French Canadian women.
18706089
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Breast cancer low-penetrance allele 1100delC in the CHEK2 gene: not present in the Chinese familial breast cancer population.
18484200
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Analysis of CHEK2 FHA domain in Czech patients with sporadic breast cancer revealed distinct rare genetic alterations.
18058223
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Absence of CHEK2 1100delC mutation in familial breast cancer cases from a South American population.
17876702
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls.
18172190
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Frequency of the CHEK2 1100delC mutation among women with breast cancer: an international study.
18381420
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
The CHEK2 1100delC mutation is not present in Korean patients with breast cancer cases tested for BRCA1 and BRCA2 mutation.
18175216
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Risk for contralateral breast cancer among carriers of the CHEK2*1100delC mutation in the WECARE Study.
18253122
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
CHEK2 mutations affecting kinase activity together with mutations in TP53 indicate a functional pathway associated with resistance to epirubicin in primary breast cancer.
18725978
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
Are the so-called low penetrance breast cancer genes, ATM, BRIP1, PALB2 and CHEK2, high risk for women with strong family histories?
18557994
2008
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
Breast cancer survival and tumor characteristics in premenopausal women carrying the CHEK2*1100delC germline mutation.
17132695
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Germline CHEK2 mutations in Jewish Ashkenazi women at high risk for breast cancer.
18085035
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
CHEK2 1100delC is prevalent in Swedish early onset familial breast cancer.
17705858
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts.
17721994
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Increased risk of breast cancer associated with CHEK2*1100delC.
16880452
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Breast cancer in patients carrying a germ-line CHEK2 mutation: Outcome after breast conserving surgery and adjuvant radiotherapy.
17250914
2007
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Breast tumors which arise in carriers of CHEK2 mutations seem to be similar to those of breast cancers in the population at large.
16914568
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Linkage disequilibrium mapping of CHEK2: common variation and breast cancer risk.
16671833
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
The CHEK2 gene and inherited breast cancer susceptibility.
16998506
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
AlteredExpression
LHGDN
Expression of checkpoint kinase 2 in breast carcinomas: correlation with key regulators of tumor cell proliferation, angiogenesis, and survival.
16437383
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
Biomarker
LHGDN
The CHEK2*1100delC allelic variant and risk of breast cancer: screening results from the Breast Cancer Family Registry.
16492927
2006
×
Entrez Id:
11200
Gene Symbol:
CHEK2
CHEK2
Mammary Neoplasms
0.500
GeneticVariation
LHGDN
Pathology and gene expression of hereditary breast tumors associated with BRCA1, BRCA2 and CHEK2 gene mutations.
16998498
2006