Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus. 17761676

2007
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Human rhinovirus attenuates the type I interferon response by disrupting activation of interferon regulatory factor 3. 16641293

2006
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Viral and therapeutic control of IFN-beta promoter stimulator 1 during hepatitis C virus infection. 16585524

2006
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Legionella pneumophila induces IFNbeta in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication. 16984921

2006
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 AlteredExpression LHGDN Analysis of genes induced by Sendai virus infection of mutant cell lines reveals essential roles of interferon regulatory factor 3, NF-kappaB, and interferon but not toll-like receptor 3. 15767394

2005
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 AlteredExpression LHGDN The host response to West Nile Virus infection limits viral spread through the activation of the interferon regulatory factor 3 pathway. 15220448

2004
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 PosttranslationalModification LHGDN Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. 12524442

2003
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death. 12829839

2003
Entrez Id: 3661
Gene Symbol: IRF3
IRF3
CUI: C3714514
Disease: Infection
Infection 		0.090 Biomarker LHGDN Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation. 11907205

2002