Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Lymphocytic infiltration and goblet cell marker alteration in the conjunctiva of the MRL/MpJ-Fas(lpr) mouse model of Sjögren's syndrome. 17208228

2007
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Unexpected development of autoimmunity in BAFF-R-mutant MRL-lpr mice. 17073941

2007
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice. 17142777

2006
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Type I IFN protects against murine lupus. 15265950

2004
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice. 12974753

2003
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Anti-DNA B cells in MRL/lpr mice show altered differentiation and editing pattern. 12486097

2002
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. 11567045

2001
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Complement C4 inhibits systemic autoimmunity through a mechanism independent of complement receptors CR1 and CR2. 11067882

2000
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Another cell death induction system: TNF-alpha acts as a ligand for Fas in vaginal cells. 10453074

1999
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease. 7628400

1995
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment. 7957574

1994
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome. 8163351

1994
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Cognitive and neurologic deficits in the MRL/lpr mouse: a clinicopathologic study. 8496852

1993
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD MRL/MP-lpr/lpr mouse as a model of immune-induced sensorineural hearing loss. 1416659

1992
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Lacrimal and salivary gland inflammation in the C3H/Ipr autoimmune strain mouse: a potential mode for Sjögren's syndrome. 1565490

1992
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. 3009614

1986
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice. 6610701

1984
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Induction of various autoantibodies by mutant gene lpr in several strains of mice. 6609979

1984
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. 6975351

1981
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. 6444324

1980
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. 762500

1979
Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome 		0.200 Biomarker MGD Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. 309911

1978