×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
The elevation of circulating fibroblast growth factor 23 without kidney disease does not increase cardiovascular disease risk.
29735309
2018
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
X-linked hypophosphatemia is the most common of the phosphate-wasting disorders mediated by elevated fibroblast growth factor 23 (FGF23) and occurs as a consequence of inactivating mutations of the PHEX gene product.
23038738
2012
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
It is known that XLH in humans and in certain mouse models is caused by inactivating mutations in PHEX /Phex (phosphate-regulating gene with homologies to endopeptidases on the X chromosome).
22573557
2012
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.
22527485
2012
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
A search for such a model led us to the Phex Hyp-Duk mouse, a mutant allele of the Phex gene causing X-linked hypophosphatemic rickets .
18289812
2008
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
A novel Phex mutation with defective glycosylation causes hypophosphatemia and rickets in mice.
17710565
2008
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes.
15976027
2005
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
X-linked hypophosphatemia (XLH ) is characterized by rickets and osteomalacia and arises from mutations in the Phex and PHEX genes in mice (Hyp) and humans, respectively.
14751570
2004
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
New intragenic deletions in the Phex gene clarify X-linked hypophosphatemia -related abnormalities in mice.
15029877
2004
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
An ethyl-nitrosourea-induced point mutation in phex causes exon skipping, x-linked hypophosphatemia, and rickets.
12414538
2002
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
Osteomalacia in hyp mice is associated with abnormal phex expression and with altered bone matrix protein expression and deposition.
11159866
2001
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Hypophosphatemic Rickets, X-Linked Dominant
1.000
Biomarker
MGD
Malabsorption of phosphate by the intestines of young X-linked hypophosphatemic mice.
3145795
1988