Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5179
Gene Symbol: PENK
PENK
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.300 Biomarker PSYGENET Surprisingly, in PENK KO mice, we did not detect anxiety and depression-related behavioral changes after the CMS procedure, and even measured a decreased hormonal stress response. 24804898

2014
Entrez Id: 5179
Gene Symbol: PENK
PENK
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.300 Biomarker PSYGENET In this study we demonstrate that, surprisingly, animals lacking enkephalin (preproenkephalin, Penk1(-/-)) showed no depression-related phenotype in the Porsolt forced swimming or tail suspension tests. 17375141

2007
Entrez Id: 5179
Gene Symbol: PENK
PENK
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.300 Biomarker PSYGENET Absence of an hypoxic depression of metabolism in preproenkephalin knockout mice. 16095981

2006
Entrez Id: 5179
Gene Symbol: PENK
PENK
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.300 Biomarker PSYGENET Fos-enkephalin signaling in the rat medial vestibular nucleus facilitates vestibular compensation. 16547969

2006