Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.340 Biomarker PSYGENET Among conventional markers of alcohol abuse, the mean corpuscular volume (MCV) of erythrocytes is prognostic of alcohol-related cancer and its predictivity increases when combined with functional polymorphisms of alcohol dehydrogenase (ADH1B [rs1229984] and ADH1C [rs698]) and the mitochondrial aldehyde dehydrogenase (ALDH2 [rs671]). 21917409

2012

Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.340 Biomarker PSYGENET In humans, genetic polymorphisms of the enzymes alcohol dehydrogenase and aldehyde dehydrogenase are also associated with alcohol drinking habits and the incidence of alcohol abuse. 15164086

2004

Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.340 Biomarker PSYGENET Positive markers identify the alcohol dehydrogenase (ADH) locus, flank the brain-derived neurotropic factor (BDNF) locus, and mark seven other regions previously linked to vulnerability to nicotine or alcohol abuse. 11704927

2001

Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.340 Biomarker PSYGENET Molecular genetic aspects of alcohol metabolism and alcoholism. 9211568

1997

Entrez Id: 10327
Gene Symbol: AKR1A1
AKR1A1
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.340 Biomarker PSYGENET Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders. 7943668

1994