Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.340 Biomarker PSYGENET Our results suggest possible involvement of the AVPR1b and CRHR1 genes in the ethiology of psychotic features in the course of affective disorders, and possible involvement of CRHR1 gene in the ethiology of bipolar disorder. 24012103

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.340 Biomarker PSYGENET These translational data suggest that genetic variation in CRHR1 affects the risk for affective disorders by influencing the function of the neural circuit underlying AT and that differences in gene expression or the protein sequence involving exon 6 may be important. 23147386

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.340 Biomarker PSYGENET Polymorphisms of CRHR1 and AVPR1b may modify susceptibility to mood disorders. 23962971

2014

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.340 Biomarker PSYGENET Deficient beta-arrestin-2-CRF(1) receptor interactions could contribute to the pathophysiology of affective disorders by inducing excessive CRF(1) receptor signaling. 17363685

2007

Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1
CUI: C0525045
Disease: Mood Disorders
Mood Disorders
0.340 Biomarker PSYGENET Dysfunctioning of corticotropin-releasing factor (CRF) and its receptors (CRF(1) and CRF(2)) has been linked to the development of stress-related disorders, such as affective disorders and drug abuse. 16611089

2006