Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker PSYGENET Association of HTR2A T102C and A-1438G polymorphisms with susceptibility to major depressive disorder: a meta-analysis. 25270656

2014
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker PSYGENET Association of the T102C polymorphism in the HTR2A gene with major depressive disorder, bipolar disorder, and schizophrenia. 24962835

2014
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker PSYGENET Our findings suggested that the 5-HTR2A rs6313 T>C polymorphism was significantly correlated with a higher response rate to antidepressants in MDD patients (allele model: OR=1.33, 95% CI=1.05-1.68, P=0.020; dominant model: OR=1.62, 95% CI=1.21-2.18, P=0.001; homozygous model: OR=1.85, 95% CI=1.18-2.90, P=0.008). 25108775

2014
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker PSYGENET Accordingly, two single nucleotide polymorphisms of the HTR2A gene (rs6314 ie His452Tyr and rs6313 ie 102C/T), which specific allelic variants may decrease 5-HT2AR-mediated transmission (as in Htr2a(-/-)mice), were studied in a sample of 485 Caucasian patients with MDD. 24801750

2014
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.600 Biomarker PSYGENET The aim of this prospective study was to examine whether the 5-HT2A receptor -1438 G/A polymorphism has functional consequences on sexual well-being in young adult men presenting with their first episode of major depressive disorder (MDD) after serotonergic antidepressant treatment. 22612784

2012