Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.240 Biomarker RGD An activated vasoconstrictive, proliferative, and fibrotic axis of the renin angiotensin system (angiotensin-converting enzyme [ACE]/angiotensin [Ang]II/AngII type 1 receptor) has been implicated in the pathophysiology of pulmonary fibrosis (PF) and pulmonary hypertension (PH). 20581171

2010

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.240 Biomarker RGD Effects on cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in the monocrotaline model of experimentally induced lung fibrosis. 17506718

2007

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0034069
Disease: Pulmonary Fibrosis
Pulmonary Fibrosis
0.240 Biomarker RGD This report summarizes our experience with the protective effects of L 158,809, an angiotensin II (ANG II) receptor blocker, and two angiotensin converting enzyme (ACE) inhibitors in the development of IPS and the role of transforming growth factor beta (TGF-beta) and of alpha-actomyosin (alpha SMA) in pathogenesis of radiation induced pulmonary fibrosis in an experimental model of bone marrow transplant (BMT). 17506716

2007