DisGeNET - a database of gene-disease associations

Source: RGD

Disease: Renal fibrosis ×

Gene: SERPINE1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5054
Gene Symbol:	SERPINE1

SERPINE1

CUI:	C0151650
Disease:	Renal fibrosis

Renal fibrosis

0.260

Biomarker

RGD

Low-dose paclitaxel ameliorates renal fibrosis by suppressing transforming growth factor-β1-induced plasminogen activator inhibitor-1 signaling.

26869361

2016

Entrez Id:	5054
Gene Symbol:	SERPINE1

SERPINE1

CUI:	C0151650
Disease:	Renal fibrosis

Renal fibrosis

0.260

Therapeutic

RGD

Effects of Bone Marrow Mesenchymal Stem Cells on Plasminogen Activator Inhibitor-1 and Renal Fibrosis in Rats with Diabetic Nephropathy.

27018336

2016