×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing.
28679633 2017
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Identification of pathogenic gene mutations in LMNA and MYBPC3 that alter RNA splicing.
28679633 2017
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Arrhythmia characterization and long-term outcomes in catecholaminergic polymorphic ventricular tachycardia.
21315846 2011
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Mutation analysis of the lamin A/C gene (LMNA) among patients with different cardiomuscular phenotypes.
14684700 2003
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Large-scale mutation screening in patients with dilated or hypertrophic cardiomyopathy: a pilot study using DGGE.
16715312 2006
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Evaluation of damaging effects of splicing mutations: validation of an in vitro method for diagnostic laboratories.
24915601 2014
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples.
27532257 2017
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Cardiac arrest and left ventricular fibrosis in a Finnish family with the lamin A/C mutation.
18031519 2008
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Genetic testing for dilated cardiomyopathy in clinical practice.
22464770 2012
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
The clinical outcome of LMNA missense mutations can be associated with the amount of mutated protein in the nuclear envelope.
29943882 2018
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Autosomal dominant Emery-Dreifuss dystrophy due to mutations in rod domain of the lamin A/C gene.
10908904 2000
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Novel mutations in the lamin A/C gene in heart transplant recipients with end stage dilated cardiomyopathy.
16537768 2006
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Overlapping syndromes in laminopathies: a meta-analysis of the reported literature.
23853504 2013
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia.
17987279 2008
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Limb-girdle muscular dystrophy with severe heart failure overlapping with lipodystrophy in a patient with LMNA mutation p.Ser334del.
27585670 2017
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
High incidence of sudden death with conduction system and myocardial disease due to lamins A and C gene mutation.
11138304 2000
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Identification of mutational hot spots in LMNA encoding lamin A/C in patients with familial dilated cardiomyopathy.
18795223 2009
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Inflammatory changes in infantile-onset LMNA-associated myopathy.
21632249 2011
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Nuclear envelope alterations in fibroblasts from patients with muscular dystrophy, cardiomyopathy, and partial lipodystrophy carrying lamin A/C gene mutations.
15372542 2004
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Novel LMNA mutations in patients with Emery-Dreifuss muscular dystrophy and functional characterization of four LMNA mutations.
20848652 2011
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Lamin A/C -Related Cardiac Disease: Late Onset With a Variable and Mild Phenotype in a Large Cohort of Patients With the Lamin A/C p.(Arg331Gln) Founder Mutation.28790152 2017
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Gender-specific differences in major cardiac events and mortality in lamin A/C mutation carriers.
23183350 2013
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
GeneticVariation
CLINVAR
Dilated cardiomyopathies caused by LMNA gene defects are highly penetrant, adult onset, malignant diseases characterized by a high rate of heart failure and life-threatening arrhythmias, predicted by New York Heart Association functional class, competitive sport activity, and type of mutation.18926329 2008
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Lamin A/C gene mutation associated with dilated cardiomyopathy with variable skeletal muscle involvement.
10662742 2000
×
Entrez Id: 4000
Gene Symbol: LMNA
LMNA
Cardiomyopathy, Dilated
0.500
CausalMutation
CLINVAR
Next-Generation Sequencing to Diagnose Muscular Dystrophy, Rhabdomyolysis, and HyperCKemia.
29382405 2018