×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China.
21080251 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
23175693 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
The genetic landscape of high-risk neuroblastoma.
23334666 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
25186627 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Malignant peritoneal mesothelioma in a patient with Li-Fraumeni syndrome.
21464421 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.
22811390 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management.
26484312 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.
24556621 2014
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
20522432 2010
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Three germline mutations in the TP53 gene.
9067756 1997
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
[Germline tp53 neomutation in a patient with Li-Fraumeni syndrome and pancreatic adenocarcinoma].
16633321 2006
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
ACMG recommendations for standards for interpretation and reporting of sequence variations: Revisions 2007.
18414213 2008
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
A specific linkage between the incidence of TP53 mutations and type of chromosomal translocations in B-precursor acute lymphoblastic leukemia cell lines.
20575032 2010
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Improving performance of multigene panels for genomic analysis of cancer predisposition.
26845104 2016
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
EFGR-mutant lung adenocarcinoma and Li-Fraumeni syndrome: report of two cases and review of the literature.
25433984 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
The p53 isoform, Δ133p53α, stimulates angiogenesis and tumour progression.
22733133 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Li-Fraumeni syndrome--a molecular and clinical review.
9218725 1997
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Germ-line mutations of the p53 tumor suppressor gene in patients with high risk for cancer inactivate the p53 protein.
1631137 1992
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Germline TP53 mutational spectrum in French Canadians with breast cancer.
25925845 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer.
25503501 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Childhood adrenocortical carcinoma as a sentinel cancer for detecting families with germline TP53 mutations.
22233476 2012
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis.
20471942 2010
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
21761402 2012
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Isolation of temperature-sensitive p53 mutations from a comprehensive missense mutation library.
14559903 2004
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Radio-induced malignancies after breast cancer postoperative radiotherapy in patients with Li-Fraumeni syndrome.
21059199 2010