Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.010 Biomarker BEFREE Opposing Regulation of Cancer Properties via KRT19-Mediated Differential Modulation of Wnt/β-Catenin/Notch Signaling in Breast and Colon Cancers. 30650643

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0008487
Disease: Chordoma
Chordoma
0.010 Biomarker BEFREE Additionally, AE1/3, EMA, and CK19 were negative, which could be used to exclude chordoma. 31849484

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0028259
Disease: Nodule
Nodule
0.010 AlteredExpression BEFREE CK19 expression was not significantly (P > 0.05) associated with any of ultrasound features of nodule. 30361909

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0038987
Disease: Sweat Gland Neoplasms
Sweat Gland Neoplasms
0.010 AlteredExpression BEFREE Five types of CK, i.e., CK7, CK8, CK17, CK18 and CK19, had markedly different expression levels in hair follicle tumor and sweat gland tumor, which were statistically significant (P<0.05). 30655849

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0040137
Disease: Thyroid Nodule
Thyroid Nodule
0.010 Biomarker BEFREE Ultrasound Risk Assessment Combined with Molecular Markers of Galectin-3, c-MET, HBME-1 and CK19 for Diagnosis of Malignant and Benign Thyroid Nodules. 30361909

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0079731
Disease: B-Cell Lymphomas
B-Cell Lymphomas
0.010 Biomarker BEFREE Furthermore, FN-treated CNE2 cells resulted in down-regulated expressions of b-cell lymphoma-2 (Bcl-2), extracellular regulated protein kinases1/2 (ERK1/2), Lamin A/C and CK19 in a dose-dependent manner, while intracellular Bax expression was elevated. 31430458

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0206623
Disease: Adenosquamous carcinoma
Adenosquamous carcinoma
0.010 Biomarker BEFREE CK19 and BerEP4 were positive in BSC and focally in ASC but negative in CC. p16 was positive in 3 (60%) of the CCs, focally positive in ASC and negative in BSC. 31548087

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0281361
Disease: Adenocarcinoma of pancreas
Adenocarcinoma of pancreas
0.010 Biomarker BEFREE In addition, we identified six genes in common (i.e., <i>ANXA2</i> [annexin A2], <i>EPHA2</i> [erythropoietin-producing hepatocellular class A2], <i>ITGB4</i> [integrin beta 4], <i>KRT19</i> [keratin type I cytoskeletal 19], <i>LGALS3</i> [galectin-3], and <i>S100A14</i> [S100 calcium binding protein A14]) between the protein-protein interaction and gene co-expression networks that may have critical functions in PAAD. 31821092

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0424295
Disease: Hyperactive behavior
Hyperactive behavior
0.010 Biomarker BEFREE MR features including targetoid appearance (p = 0.001) was more frequently observed while non-peripheral "washout" (p < 0.0001) and non-rim arterial phase hyper-enhancement (p < 0.0001) were found less frequently in CK19-positive HCCs compared to CK19-negative HCCs. 30927962

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0585362
Disease: Squamous cell carcinoma of mouth
Squamous cell carcinoma of mouth
0.010 Biomarker BEFREE In this study, we evaluated squamous cell carcinoma antigen (SCC-Ag), cytokeratin 19 fragment (CYFRA 21-1) and C-reactive protein (CRP) simultaneously in oral cavity squamous cell carcinoma (OSCC) patients. 30952746

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0859920
Disease: Hair Follicle Neoplasm
Hair Follicle Neoplasm
0.010 AlteredExpression BEFREE Five types of CK, i.e., CK7, CK8, CK17, CK18 and CK19, had markedly different expression levels in hair follicle tumor and sweat gland tumor, which were statistically significant (P<0.05). 30655849

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0878500
Disease: Intraepithelial Neoplasia
Intraepithelial Neoplasia
0.010 Biomarker BEFREE Higher CK19 and lower CK16 scores were associated with adjacent epithelial dysplasia. 30579132

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.010 AlteredExpression BEFREE PTEN plays a key role in hepatocarcinogenesis and reduction of PTEN expression is related to increased expression of CD133, EpCAM and CK19, which is a useful tool to evaluate HCC prognosis and recurrence. 31126975

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C2711227
Disease: Steatohepatitis
Steatohepatitis
0.010 Biomarker BEFREE Positive expression of CD133, EpCAM and CK19 was correlated with steatosis, moderate to poor differentiation, and so on. 31126975

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C4744444
Disease: Metastatic Lung Adenocarcinoma
Metastatic Lung Adenocarcinoma
0.010 Biomarker BEFREE To examine the serum levels of carcinoembryonic antigen (CEA), cytokeratin-19 fragments (CYFRA21-1), neuron-specific enolase (NSE), carbohydrate antigen (CA) 19-9, CA125, tissue polypeptide antigen (TPA), tissue polypeptide specific antigen (TPS), and lactate dehydrogenase (LDH) to predict de novo metastatic lung adenocarcinoma. 31356196

2019

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0008370
Disease: Cholestasis
Cholestasis
0.010 Biomarker BEFREE Bile duct obstruction was detected by hematoxylin and eosin staining and CK-19 immunohistochemical staining. 30196281

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0008373
Disease: Cholesteatoma
Cholesteatoma
0.010 Biomarker BEFREE KRT19 with a tumor suppressor potential might restrict the recurrence of cholesteatoma. 30021014

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE The effects of aerobic exercise frequencies on liver fibrosis, α-fetoprotein and cytokeratin 19 in experimental type 2 diabetes-induced rats: an immunohistochemistry study. 30260236

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0013274
Disease: Patent ductus arteriosus
Patent ductus arteriosus
0.010 AlteredExpression BEFREE We found that livers from patients and mice with PDA harbor single disseminated cancer cells (DCCs) lacking expression of cytokeratin 19 (CK19) and major histocompatibility complex class I (MHCI). 29773669

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0026837
Disease: Muscle Rigidity
Muscle Rigidity
0.010 Biomarker BEFREE Cytokeratin 19 (<i>KRT19</i>) is a cytoplasmic intermediate filament protein, which is responsible for structural rigidity and multipurpose scaffolds. 29747452

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0149782
Disease: Squamous cell carcinoma of lung
Squamous cell carcinoma of lung
0.010 Biomarker BEFREE The combination of the blood based tumor biomarkers cytokeratin 19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as a potential predictor of benefit from adjuvant chemotherapy in early stage squamous cell carcinoma of the lung (SCC). 29748014

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0238339
Disease: Hereditary pancreatitis
Hereditary pancreatitis
0.010 AlteredExpression BEFREE HPC phenotype expression as denoted by CK19 and Sox9 staining was detected in the liver tissue with ACR. 29345755

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0239946
Disease: Fibrosis, Liver
Fibrosis, Liver
0.010 Biomarker BEFREE BMP-2 gene delivery alleviated the elevations of serum hepatic enzymes, cholangiocyte marker CK19, HSC activation markers, and liver fibrosis in both models. 29789683

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0280217
Disease: stage, non-small cell lung cancer
stage, non-small cell lung cancer
0.010 Biomarker BEFREE To determine whether the tumor biomarkers cytokeratin 19 fragment (CYFRA 21-1) and carcinoembryonic antigen (CEA), which are prognostic in early-stage non-small cell lung cancer (NSCLC), can predict which patients benefit from adjuvant chemotherapy (CTx). 29748014

2018

Entrez Id: 3880
Gene Symbol: KRT19
KRT19
CUI: C0280255
Disease: stage, endometrial carcinoma
stage, endometrial carcinoma
0.010 AlteredExpression BEFREE One-Step Nucleic Acid Amplification (OSNA): A fast molecular test based on CK19 mRNA concentration for assessment of lymph-nodes metastases in early stage endometrial cancer. 29698418

2018