Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 4087
Gene Symbol: SMAD2
SMAD2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation UNIPROT

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker CTD_human

Entrez Id: 6714
Gene Symbol: SRC
SRC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.390 Biomarker CTD_human

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.360 Biomarker CTD_human

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.350 Biomarker CTD_human

Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.320 Biomarker CTD_human

Entrez Id: 2033
Gene Symbol: EP300
EP300
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.320 Biomarker CTD_human

Entrez Id: 201163
Gene Symbol: FLCN
FLCN
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 Biomarker CTD_human

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.310 Biomarker CTD_human

Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.300 Biomarker CTD_human

Entrez Id: 2184
Gene Symbol: FAH
FAH
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 Biomarker BEFREE Although the level of N-AcO-2-FAA that bound to mononuclear leukocyte DNA was the same for the various population groups, the level of N-AcO-2-FAA-induced unscheduled DNA synthesis (UDS) was significantly reduced in the mononuclear leukocytes of individuals who had had colorectal cancer or a genetic predisposition for the disease. 6573531

1983

Entrez Id: 2175
Gene Symbol: FANCA
FANCA
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 Biomarker BEFREE Although the level of N-AcO-2-FAA that bound to mononuclear leukocyte DNA was the same for the various population groups, the level of N-AcO-2-FAA-induced unscheduled DNA synthesis (UDS) was significantly reduced in the mononuclear leukocytes of individuals who had had colorectal cancer or a genetic predisposition for the disease. 6573531

1983

Entrez Id: 50
Gene Symbol: ACO2
ACO2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 Biomarker BEFREE Although the level of N-AcO-2-FAA that bound to mononuclear leukocyte DNA was the same for the various population groups, the level of N-AcO-2-FAA-induced unscheduled DNA synthesis (UDS) was significantly reduced in the mononuclear leukocytes of individuals who had had colorectal cancer or a genetic predisposition for the disease. 6573531

1983

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression BEFREE The c-myc protein is constitutively expressed at elevated levels in colorectal carcinoma cell lines. 3283655

1988

Entrez Id: 2956
Gene Symbol: MSH6
MSH6
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 Biomarker BEFREE Increasing recognition of the statistical burden posed by HNPCC (5 to 6 percent of all colorectal cancer) mandates that physicians have a better understanding of the genetics, natural history, and distinction between the hereditary site-specific variant (Lynch syndrome I) and the Cancer Family Syndrome (Lynch syndrome II). 3366037

1988

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.090 GeneticVariation BEFREE Ha-ras restriction fragment length polymorphisms in colorectal cancer. 2896015

1988

Entrez Id: 5314
Gene Symbol: PKHD1
PKHD1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.020 GeneticVariation BEFREE Familial polyposis coli (FPC) is caused by an autosomal dominant gene on chromosome 5, and it has been proposed that colorectal cancer in the general population arises from loss or inactivation of the FPC gene, analogous to recessive tumor genes in retinoblastoma and Wilms' tumor. 2841761

1988

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 Biomarker BEFREE Thus we present evidence that in colorectal cancer only a small proportion of tumor-infiltrating macrophages produces TNF, indicating that the microenvironment of the tumor provides adequate, yet suboptimal, conditions for macrophage activation. 2662193

1989

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.400 GeneticVariation BEFREE Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. 2649981

1989

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.100 AlteredExpression BEFREE The results show that a considerable proportion of colorectal carcinomas is heterogeneous with regard to HLA-A and HLA-B expression. 2462591

1989

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression BEFREE The results show that a considerable proportion of colorectal carcinomas is heterogeneous with regard to HLA-A and HLA-B expression. 2462591

1989

Entrez Id: 2249
Gene Symbol: FGF4
FGF4
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE No coamplification of the hst-1 and int-2 genes was detected in gastric carcinomas and colorectal carcinomas. 2529025

1989

Entrez Id: 57508
Gene Symbol: INTS2
INTS2
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.010 GeneticVariation BEFREE No coamplification of the hst-1 and int-2 genes was detected in gastric carcinomas and colorectal carcinomas. 2529025

1989