Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0153633
Disease: Malignant neoplasm of brain
Malignant neoplasm of brain 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0496899
Disease: Benign neoplasm of brain, unspecified
Benign neoplasm of brain, unspecified 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0750974
Disease: Brain Tumor, Primary
Brain Tumor, Primary 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0750977
Disease: Recurrent Brain Neoplasm
Recurrent Brain Neoplasm 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0750979
Disease: Primary malignant neoplasm of brain
Primary malignant neoplasm of brain 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C1527390
Disease: Neoplasms, Intracranial
Neoplasms, Intracranial 		0.300 Biomarker CTD_human A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth. 27935819

2017
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0238198
Disease: Gastrointestinal Stromal Tumors
Gastrointestinal Stromal Tumors 		0.300 Biomarker CTD_human Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. 27793025

2016
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C3179349
Disease: Gastrointestinal Stromal Sarcoma
Gastrointestinal Stromal Sarcoma 		0.300 Biomarker CTD_human Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression. 27793025

2016
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0920269
Disease: Microsatellite Instability
Microsatellite Instability 		0.300 Biomarker CTD_human Gene targets of frameshift mutations caused by MSI are involved in various cellular functions, including DNA repair (MSH3 and MSH6), cell signaling (TGFBR2 and ACVR2A), apoptosis (BAX), epigenetic regulation (HDAC2 and ARID1A), and miRNA processing (TARBP2 and XPO5), and a subset of MSI+ CRCs reportedly shows the mutated miRNA machinery phenotype. 25701956

2015
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C1721098
Disease: Replication Error Phenotype
Replication Error Phenotype 		0.300 Biomarker CTD_human Microsatellite instability: an update. 25701956

2015
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0034067
Disease: Pulmonary Emphysema
Pulmonary Emphysema 		0.300 Biomarker GENOMICS_ENGLAND TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development? 23161884

2013
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0005940
Disease: Bone Diseases
Bone Diseases 		0.300 Biomarker CTD_human Germline TGF-beta receptor mutations and skeletal fragility: a report on two patients with Loeys-Dietz syndrome. 20358619

2010
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0005967
Disease: Bone neoplasms
Bone neoplasms 		0.300 Therapeutic CTD_human Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer. 16489006

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0007852
Disease: Cervical Migraine Syndrome
Cervical Migraine Syndrome 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0015393
Disease: Eye Abnormalities
Eye Abnormalities 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0018984
Disease: Hemicrania migraine
Hemicrania migraine 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0019295
Disease: Inguinal Hernia, Direct
Inguinal Hernia, Direct 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0019296
Disease: Inguinal Hernia, Indirect
Inguinal Hernia, Indirect 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0270858
Disease: Abdominal Migraine
Abdominal Migraine 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0279530
Disease: Malignant Bone Neoplasm
Malignant Bone Neoplasm 		0.300 Therapeutic CTD_human Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer. 16489006

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0338489
Disease: Status Migrainosus
Status Migrainosus 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0376634
Disease: Craniofacial Abnormalities
Craniofacial Abnormalities 		0.300 Biomarker CTD_human TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development. 16368934

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0376634
Disease: Craniofacial Abnormalities
Craniofacial Abnormalities 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
CUI: C0521664
Disease: Acute Confusional Migraine
Acute Confusional Migraine 		0.300 Biomarker CTD_human Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. 16885183

2006