Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4018
Gene Symbol: LPA
LPA
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.100 GeneticVariation BEFREE <i>Objectives.</i> Evidence from case-control studies as well as meta-analyses of these study designs suggest elevated lipoprotein(a) [Lp(a)] to be associated with an increased risk of venous thromboembolism (VTE). 31032650

2019

Entrez Id: 23583
Gene Symbol: SMUG1
SMUG1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.030 Biomarker BEFREE <sup>18</sup>F-Fluorodesoxyglucose Positron-Emission-Tomography combined with Computed-Tomography (FDG PET/CT) might be an attractive tool for cancer screening in patients with venous thromboembolism (VTE), allowing non-invasive whole-body imaging. 28460260

2017

Entrez Id: 213
Gene Symbol: ALB
ALB
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.080 Biomarker BEFREE (1) The use of LMWH for VTE prophylaxis (per cent ICU days) and albumin for fluid resuscitation (per cent of patients); and (2) provider knowledge of evidence underpinning these practices, and barriers and facilitators to adopt and de-adopt these practices. 30878979

2019

Entrez Id: 2152
Gene Symbol: F3
F3
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.100 Biomarker BEFREE : Microvesicles associated with tissue factor (TF) may play a role in cancer-related venous thromboembolism; however, not much is known about their interaction with the tumour stroma, especially the endothelium or any procoagulant changes seen because of this interaction. 27841803

2017

Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Venous thromboembolism at a young age in a brother and sister with coinheritance of homozygous 20210A/A prothrombin mutation and heterozygous 1691G/A factor V Leiden mutation. 10456622

1999

Entrez Id: 465
Gene Symbol: ATD
ATD
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease and antithrombin deficiency [ATD] constitutes a major risk factor. 24966143

2014

Entrez Id: 27019
Gene Symbol: DNAI1
DNAI1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease and protein C deficiency [PCD] constitutes a major risk factor. 25039884

2014

Entrez Id: 5092
Gene Symbol: PCBD1
PCBD1
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease and protein C deficiency [PCD] constitutes a major risk factor. 25039884

2014

Entrez Id: 352909
Gene Symbol: DNAAF3
DNAAF3
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease and protein C deficiency [PCD] constitutes a major risk factor. 25039884

2014

Entrez Id: 1767
Gene Symbol: DNAH5
DNAH5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease and protein C deficiency [PCD] constitutes a major risk factor. 25039884

2014

Entrez Id: 5662
Gene Symbol: PSD
PSD
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 Biomarker BEFREE Venous thromboembolism [TE] is a multifactorial disease, and protein S deficiency [PSD] constitutes a major risk factor. 25272994

2015

Entrez Id: 406942
Gene Symbol: MIR150
MIR150
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.010 GeneticVariation BEFREE Venous thromboembolism (VTE), encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE), is the third most common cardiovascular disease. miR-150 is one of important microRNAs which play critical role in various cellular function such as endothelial progenitor cells (EPCs). 30315850

2019

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden (Arg506Gln), a confounding genetic risk factor but not mandatory for the occurrence of venous thromboembolism in homozygotes and obligate heterozygotes for cystathionine beta-synthase deficiency. 10235428

1999

Entrez Id: 5624
Gene Symbol: PROC
PROC
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.400 GeneticVariation BEFREE Activated protein C (APC) resistance, due to a point mutation in the factor V gene (FV:Q506), is a major risk factor for venous thromboembolism. 10235434

1999

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden and prothrombin variant G20210A occur frequently in patients with venous thromboembolism. 10987590

2000

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 Biomarker BEFREE Factor V Leiden (FVL)-carrying relatives of selected patients with venous thromboembolism (VTE) have much higher venous thrombotic risks than FVL-carrying relatives of unselected consecutive patients with VTE. 11529860

2001

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden (FVL) and the prothrombin 20210A (PT-20210A) variant are well-known risk factors for venous thromboembolism (VT). 11738073

2001

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.030 AlteredExpression BEFREE APC levels <0.69 ng/ml increased the risk of a single or recurrent episode of VTE 4.2-fold (95% confidence interval, 2.0-9.0) or 6.9-fold (2.6-17.9). respectively, and APC levels <0.77 ng/ml increased these risks 3.4-fold (1.9-6.2) or 5.1-fold (2.3-11.2), respectively, compared with controls. 11776301

2001

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden and factor V R2 allele: high-throughput analysis and association with venous thromboembolism. 11816705

2001

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden (G1691A) and prothrombin gene G20210A mutations as potential risk factors for venous thromboembolism after total hip or total knee replacement surgery. 12008938

2002

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 GeneticVariation BEFREE Factor V Leiden and prothrombin gene G20210A mutation in children with venous thromboembolism. 12083504

2002

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 Biomarker LHGDN Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia. 12221665

2002

Entrez Id: 5624
Gene Symbol: PROC
PROC
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.400 Biomarker BEFREE Activated protein C (APC) resistance is a common risk factor for venous thromboembolism (VTE) attributed to various mechanisms, including factor V Leiden (FVL) polymorphism. 12520697

2003

Entrez Id: 2153
Gene Symbol: F5
F5
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 Biomarker BEFREE FVL was found with a frequency of 1.5% and 2.7% in the VTE and non-VTE group, respectively (odds ratio [OR] for VTE 0.6, 95% CI: 0.06-5.3). 12757770

2003

Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C1861172
Disease: Venous Thromboembolism
Venous Thromboembolism
0.500 AlteredExpression BEFREE Prothrombin levels were measured by a chromogenic assay in 152 women who suffered from VTE in reproductive age and in 296 healthy women. 12871547

2003