×
Entrez Id:
26191
Gene Symbol:
PTPN22
PTPN22
Rheumatoid Arthritis
0.700
Biomarker
HPO
×
Entrez Id:
6583
Gene Symbol:
SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
Biomarker
CTD_human
×
Entrez Id:
6583
Gene Symbol:
SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
Biomarker
HPO
×
Entrez Id:
3663
Gene Symbol:
IRF5
IRF5
Rheumatoid Arthritis
0.500
CausalMutation
CLINVAR
×
Entrez Id:
23569
Gene Symbol:
PADI4
PADI4
Rheumatoid Arthritis
0.500
Biomarker
HPO
×
Entrez Id:
3586
Gene Symbol:
IL10
IL10
Rheumatoid Arthritis
0.500
Biomarker
HPO
×
Entrez Id:
23569
Gene Symbol:
PADI4
PADI4
Rheumatoid Arthritis
0.500
GeneticVariation
CLINVAR
×
Entrez Id:
4261
Gene Symbol:
CIITA
CIITA
Rheumatoid Arthritis
0.500
SusceptibilityMutation
CLINVAR
×
Entrez Id:
4261
Gene Symbol:
CIITA
CIITA
Rheumatoid Arthritis
0.500
Biomarker
HPO
×
Entrez Id:
4261
Gene Symbol:
CIITA
CIITA
Rheumatoid Arthritis
0.500
Biomarker
CTD_human
×
Entrez Id:
4795
Gene Symbol:
NFKBIL1
NFKBIL1
Rheumatoid Arthritis
0.470
Biomarker
HPO
×
Entrez Id:
4795
Gene Symbol:
NFKBIL1
NFKBIL1
Rheumatoid Arthritis
0.470
Biomarker
CTD_human
×
Entrez Id:
51744
Gene Symbol:
CD244
CD244
Rheumatoid Arthritis
0.440
SusceptibilityMutation
CLINVAR
×
Entrez Id:
51744
Gene Symbol:
CD244
CD244
Rheumatoid Arthritis
0.440
Biomarker
HPO
×
Entrez Id:
1777
Gene Symbol:
DNASE2
DNASE2
Rheumatoid Arthritis
0.230
Biomarker
MGD
×
Entrez Id:
1282
Gene Symbol:
COL4A1
COL4A1
Rheumatoid Arthritis
0.110
CausalMutation
CLINVAR
×
Entrez Id:
55578
Gene Symbol:
SUPT20H
SUPT20H
Rheumatoid Arthritis
0.110
SusceptibilityMutation
CLINVAR
×
Entrez Id:
2643
Gene Symbol:
GCH1
GCH1
Rheumatoid Arthritis
0.100
Biomarker
HPO
×
Entrez Id:
6902
Gene Symbol:
TBCA
TBCA
Rheumatoid Arthritis
0.020
Biomarker
BEFREE
<b>:</b> To study new target-oriented molecules that are active against rheumatoid arthritis -dependent pain, new dual inhibitors incorporating both a carbonic anhydrase (CA)-binding moiety and a cyclooxygenase inhibitor (NSAID) were tested in a rat model of rheumatoid arthritis induced by CFA intra-articular (i.a.) injection.
31003542
2019
×
Entrez Id:
706
Gene Symbol:
TSPO
TSPO
Rheumatoid Arthritis
0.050
Biomarker
BEFREE
<b>Abbreviations:</b> 3-MA: 3-methyladenine; ACPA: anti-citrullinated peptide antibodies; anti-CCP: anti-cyclic citrullinated peptide antibody; cVIM: citrullinated VIM; BECN1: beclin1; DAPI: 4',6-diamidino-2-phenylindole; FBS: fetal bovine serum; HLA: human leukocyte antigen; IFNG/IFN-γ: interferon gamma; IL6: interleukin 6; IP: immunoprecipitation; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence index; MHC: major histocompatibility complex; OA: osteoarthritis; PADI: peptidyl arginine deiminase; PepA: pepstatin A; PBS : phosphate-buffered saline; PtdIns3K: phosphatidylinositol 3-kinase; RA : rheumatoid arthritis ; SFs: synovial fibroblasts; siRNA: small interfering RNA; VIM: vimentin.
31486697
2020
×
Entrez Id:
1131
Gene Symbol:
CHRM3
CHRM3
Rheumatoid Arthritis
0.010
Biomarker
BEFREE
<b>Abbreviations:</b> 3-MA: 3-methyladenine; ACPA: anti-citrullinated peptide antibodies; anti-CCP: anti-cyclic citrullinated peptide antibody; cVIM: citrullinated VIM; BECN1: beclin1; DAPI: 4',6-diamidino-2-phenylindole; FBS: fetal bovine serum; HLA: human leukocyte antigen; IFNG/IFN-γ: interferon gamma; IL6: interleukin 6; IP: immunoprecipitation; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFI: mean fluorescence index; MHC: major histocompatibility complex; OA: osteoarthritis; PADI: peptidyl arginine deiminase; PepA: pepstatin A; PBS : phosphate-buffered saline; PtdIns3K: phosphatidylinositol 3-kinase; RA : rheumatoid arthritis ; SFs: synovial fibroblasts; siRNA: small interfering RNA; VIM: vimentin.
31486697
2020
×
Entrez Id:
5132
Gene Symbol:
PDC
PDC
Rheumatoid Arthritis
0.020
Biomarker
BEFREE
<b>Abbreviations:</b> AA: Alopecia areata; AIRE: Autoimmune Regulator; APECED: Autoimmune, Polyendocrinopathy Candidiasis Ectodermal Dystrophy; DLQI: Dermatology life quality index questionnaire; MIQE: Minimum information for publication of quantitative real-time PCR experiments; mTEC: Medullary thymic epithelial cells; PHD : Plant homeodomain; qRT-PCR: Quantitative reversetranscription-polymerase chain reaction; RA: Rheumatoid arthritis .
31601134
2020
×
Entrez Id:
1055
Gene Symbol:
CECR
CECR
Rheumatoid Arthritis
0.010
GeneticVariation
BEFREE
<b>Aim:</b> To study if cumulative glucocorticoid use could be related to cognitive impairment in rheumatoid arthritis (RA ) patients.<b>Methods:</b> A sample of 60 RA patients and 64 controls were studied for the Mini Mental State Examination (MMSE) and depression scale (using CES -D or Center for Epidemiological Studies Depression scale).
31625439
2019
×
Entrez Id:
7124
Gene Symbol:
TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
BEFREE
<b>Conclusion</b>: TNFα antagonists are used less often and glucocorticoids more often in elderly patients with active RA compared to their younger counterparts.
30230962
2018
×
Entrez Id:
23569
Gene Symbol:
PADI4
PADI4
Rheumatoid Arthritis
0.500
Biomarker
BEFREE
<b>Conclusion</b>: Serum capacity to activate PAD4 was associated with ACPA and RF positivity and earlier disease onset in early RA patients, and decreased after initiation of DMARD treatment, indicating that anti-PAD treatment could potentially be beneficial in RA .
31544586
2020