DisGeNET - a database of gene-disease associations

Source: GWASCAT

Disease: C-reactive protein measurement ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	9745
Gene Symbol:	ZNF536

ZNF536

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genome-wide association with select biomarker traits in the Framingham Heart Study.

17903293

2007

Entrez Id:	3953
Gene Symbol:	LEPR

LEPR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008

Entrez Id:	348
Gene Symbol:	APOE

APOE

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008

Entrez Id:	3570
Gene Symbol:	IL6R

IL6R

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008

Entrez Id:	6927
Gene Symbol:	HNF1A

HNF1A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008

Entrez Id:	6927
Gene Symbol:	HNF1A

HNF1A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

18439552

2008

Entrez Id:	64897
Gene Symbol:	C12orf43

C12orf43

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

18439552

2008

Entrez Id:	10452
Gene Symbol:	TOMM40

TOMM40

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.

18439552

2008

Entrez Id:	3570
Gene Symbol:	IL6R

IL6R

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

19567438

2009

Entrez Id:	6927
Gene Symbol:	HNF1A

HNF1A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

19567438

2009

Entrez Id:	3953
Gene Symbol:	LEPR

LEPR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.

19567438

2009

Entrez Id:	6927
Gene Symbol:	HNF1A

HNF1A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.

21196492

2011

Entrez Id:	256227
Gene Symbol:	STEAP1B

STEAP1B

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus.

21196492

2011

Entrez Id:	3570
Gene Symbol:	IL6R

IL6R

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	5771
Gene Symbol:	PTPN2

PTPN2

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	9275
Gene Symbol:	BCL7B

BCL7B

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	2646
Gene Symbol:	GCKR

GCKR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	3172
Gene Symbol:	HNF4A

HNF4A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	6095
Gene Symbol:	RORA

RORA

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	101928784
Gene Symbol:	RORA-AS1

RORA-AS1

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	222545
Gene Symbol:	GPRC6A

GPRC6A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	6927
Gene Symbol:	HNF1A

HNF1A

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	114548
Gene Symbol:	NLRP3

NLRP3

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.

21300955

2011

Entrez Id:	283460
Gene Symbol:	HNF1A-AS1

HNF1A-AS1

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.100

GeneticVariation

GWASCAT

Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.

21647738

2012