Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55
Gene Symbol: ACPP
ACPP
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 AlteredExpression BEFREE Expression of prostatic acid phosphatase in human prostate cancer. 7296542

1982

Entrez Id: 133418
Gene Symbol: EMB
EMB
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 Biomarker BEFREE A human prostate carcinoma line that had not been grown in the athymic mice was found to have no gp70, but was shown to be able to synthesize gp70 after a single passage in the athymic mice. 6307513

1983

Entrez Id: 3458
Gene Symbol: IFNG
IFNG
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Interferon-gamma (IFN-gamma) production by peripheral blood leukocytes from bladder cancer patients was compared with that of patients with prostate cancer and benign prostatic hyperplasia, nontumor-bearing patients with bacterial infections, and normal controls. 6426791

1984

Entrez Id: 2638
Gene Symbol: GC
GC
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 GeneticVariation BEFREE The distribution of phenotypes and gene frequencies of the third component of complement (C3), group-specific component (Gc), haptoglobin (Hp) and transferrin (Tf) were studied in 115 patients with carcinoma of the prostate. 6596192

1985

Entrez Id: 3240
Gene Symbol: HP
HP
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 GeneticVariation BEFREE The distribution of phenotypes and gene frequencies of the third component of complement (C3), group-specific component (Gc), haptoglobin (Hp) and transferrin (Tf) were studied in 115 patients with carcinoma of the prostate. 6596192

1985

Entrez Id: 83733
Gene Symbol: SLC25A18
SLC25A18
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 Biomarker BEFREE On the contrary, a statistically significant association was found between carcinoma of prostate and C3F and Gc2 genes. 6596192

1985

Entrez Id: 2160
Gene Symbol: F11
F11
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 Biomarker BEFREE An inhibitor of plasma thromboplastin antecedent (PTA, factor XI), measured in coagulant and radioimmunoassays, was detected in a 60-year-old man with carcinoma of the prostate who had no evidence of a bleeding tendency. 3486671

1986

Entrez Id: 171558
Gene Symbol: PTCRA
PTCRA
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.010 Biomarker BEFREE An inhibitor of plasma thromboplastin antecedent (PTA, factor XI), measured in coagulant and radioimmunoassays, was detected in a 60-year-old man with carcinoma of the prostate who had no evidence of a bleeding tendency. 3486671

1986

Entrez Id: 5340
Gene Symbol: PLG
PLG
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Plasminogen activators in human prostate cancer cell lines and tumors: correlation with the aggressive phenotype. 2659823

1989

Entrez Id: 2247
Gene Symbol: FGF2
FGF2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 AlteredExpression BEFREE Expression of basic fibroblast growth factor mRNA in benign prostatic hyperplasia and prostatic carcinoma. 2463616

1989

Entrez Id: 1950
Gene Symbol: EGF
EGF
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Prostate carcinoma contained higher concentrations of EGF receptors based on DNA than did BPH, although it is accepted that BPH may not be the appropriate comparison for carcinoma. 2468269

1989

Entrez Id: 3479
Gene Symbol: IGF1
IGF1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Specimens of benign prostatic hypertrophy (BPH) and prostate carcinoma and prostate cells in culture were assessed for their capacity to bind androgens, radioiodinated EGF, and IGF-I, and to express certain cellular protooncogenes. 2468269

1989

Entrez Id: 2246
Gene Symbol: FGF1
FGF1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 AlteredExpression BEFREE Using Northern blot analysis we now show that the messenger RNA for bFGF but not aFGF is expressed in benign prostatic hyperplastic (BPH) tissue as well as in carcinoma of the prostate (CAP). 2463616

1989

Entrez Id: 367
Gene Symbol: AR
AR
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 AlteredExpression BEFREE Androgen receptor gene expression in human prostate carcinoma cell lines. 2386943

1990

Entrez Id: 57126
Gene Symbol: CD177
CD177
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.040 AlteredExpression BEFREE The highest levels of EGF-R mRNA were found in the human prostatic carcinoma cell lines, PC-3 and DU145. 1692888

1990

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.200 Biomarker BEFREE DNA ploidy and prostate-specific antigen as prognostic factors in clinically resectable prostate cancer. 1710533

1991

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. 1873816

1991

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 GeneticVariation BEFREE Our data suggest that tumor suppressor genes involved in the oncogenesis of prostatic carcinoma may be localized between 8 pter and the PLAT locus and that additional/alternative tumor suppressor genes may be localized on chromosome 10 and on the long arm of chromosome 16 distal to the D16S4 locus. 1868037

1991

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.030 GeneticVariation BEFREE In this paper, we report a comprehensive screening of 19 CaPs and 3 CaP cell lines for activating point mutations in the sequences of the 12th and 61st codons of c-Ha-ras-1 and the c-Ki-ras-2 genes, as well as the 12th, 13th, and 61st codons of the c-N-ras gene. 1998954

1991

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.200 Biomarker BEFREE Quantitative estimation of tissue prostate specific antigen, deoxyribonucleic acid ploidy and cytological grade in fine needle aspiration biopsies for prognosis of hormonally treated prostatic carcinoma. 1380992

1992

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.200 Biomarker BEFREE In order to elucidate the mechanism of androgen-regulation of genes expressed only in the prostate gland, the effects of steroid hormones on the biosynthesis and secretion of human prostatic acid phosphatase (PAP) and prostate-specific antigen (PSA) were studied in the human prostatic carcinoma cell line, LNCaP. 1373297

1992

Entrez Id: 354
Gene Symbol: KLK3
KLK3
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.200 Biomarker BEFREE Prostate-specific antigen (PSA) has emerged as the most useful marker for management of patients with prostate cancer. 1379363

1992

Entrez Id: 2247
Gene Symbol: FGF2
FGF2
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Basic fibroblast growth factor in human prostate cancer cells. 1732045

1992

Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 AlteredExpression BEFREE Cyclic AMP induces transforming growth factor beta 2 gene expression and growth arrest in the human androgen-independent prostate carcinoma cell line PC-3. 1373503

1992

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.100 Biomarker BEFREE Accumulation of p53 confers proliferative advantage for prostatic carcinoma cells and defines a small subgroup of highly malignant carcinomas. 1350643

1992