×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
GeneticVariation
BEFREE
Hypertension and severe hypokalaemia associated with ectopic ACTH production.30115708 2018
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
BEFREE
Hypertension occurred in 34/77 children (44%) during treatment with ACTH and 4/11 children (36%) during treatment with prednisolone.31769329 2020
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
BEFREE
ACTH = adrenocorticotropic hormone ; AIx@75 = augmentation index corrected for a heart rate of 75 beats per minute; BMI = body mass index; CVD = cardiovascular disease; DBP = diastolic blood pressure; FSH = follicle-stimulating hormone; GH = growth hormone; HT = hypertension ; IGF-1 = insulin-like growth factor 1; LH = luteinizing hormone; MBP = mean blood pressure; MRI = magnetic resonance imaging; NFPA = nonfunctioning pituitary adenoma; PP = pulse pressure; PWA = pulse wave analysis; PWV = pulse wave velocity; SBP = systolic blood pressure; TSH = thyroid-stimulating hormone.29975581 2018
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
BEFREE
A 45-year-old woman with adrenocorticotropin (ACTH )-independent hypercortisolism, diabetes mellitus, and hypertension had undergone left adrenalectomy for ACTH-independent Cushing's syndrome 20 years prior to this presentation.
12670039 2002
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Accordingly we hypothesized that ACTH -induced hypertension would be reversed by BH4 supplementation.
15132301 2004
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Accordingly we hypothesized that ACTH -induced hypertension would be reversed by BH4 supplementation.
15132301 2004
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
ACTH hypertension in the rat: role of kidney and gonads.
1664305 1991
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
ACTH hypertension in the rat: role of kidney and gonads.
1664305 1991
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
ACTH hypertension in the rat: role of sodium chloride.
1321011 1992
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
ACTH hypertension in the rat: role of sodium chloride.
1321011 1992
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
ACTH therapy in infantile spasms: side effects.
6254450 1980
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
ACTH therapy in infantile spasms: side effects.
6254450 1980
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Acute glucocorticoid (corticosterone) hypertension in the rate is significantly attenuated by neomycin administration (Honour 1981), as is ACTH -induced hypertension is the same species (Honour & Kent 1981) presumably by altering gut bacterial steroid metabolism.
6097376 1985
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Acute glucocorticoid (corticosterone) hypertension in the rate is significantly attenuated by neomycin administration (Honour 1981), as is ACTH -induced hypertension is the same species (Honour & Kent 1981) presumably by altering gut bacterial steroid metabolism.
6097376 1985
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Adrenocorticotrophic hormone-induced hypertension in the rat: effects of the endothelin antagonist bosentan.
10474778 1999
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Adrenocorticotrophic hormone-induced hypertension in the rat: effects of the endothelin antagonist bosentan.
10474778 1999
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Adrenocorticotrophin-induced hypertension in rats. Role of progesterone and digoxin-like substances.
8136112 1994
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Adrenocorticotrophin-induced hypertension in rats. Role of progesterone and digoxin-like substances.
8136112 1994
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Adrenocorticotrophin-induced hypertension in the rat: haemodynamic, metabolic and morphological characteristics.
2157753 1990
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Adrenocorticotrophin-induced hypertension in the rat: haemodynamic, metabolic and morphological characteristics.
2157753 1990
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism.
10100081 1999
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
Adrenocorticotrophin-induced hypertension: effects of mineralocorticoid and glucocorticoid receptor antagonism.
10100081 1999
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
GeneticVariation
BEFREE
Adrenocorticotropic hormone (ACTH )-secreting tumors account for 2% to 6% of adenomas and are associated with obesity, hypertension , diabetes, and other morbidity.
28170483 2017
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
After 25 days (range 13 to 46) of treatment with ACTH , systolic blood pressure increased from 93 +/- 9 to 118 +/- 20 mm Hg (p < 0.001; mean +/- 1 SD).
8279378 1994
×
Entrez Id: 5443
Gene Symbol: POMC
POMC
Hypertensive disease
0.400
Therapeutic
CTD_human
After 25 days (range 13 to 46) of treatment with ACTH , systolic blood pressure increased from 93 +/- 9 to 118 +/- 20 mm Hg (p < 0.001; mean +/- 1 SD).
8279378 1994