Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0003496
Disease: Aortic Rupture
Aortic Rupture 		0.300 Biomarker CTD_human Bone marrow from blotchy mice is dispensable to regulate blood copper and aortic pathologies but required for inflammatory mediator production in LDLR-deficient mice during chronic angiotensin II infusion. 25449986

2015
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0019189
Disease: Hepatitis, Chronic
Hepatitis, Chronic 		0.300 Biomarker CTD_human Aberrant expression of copper associated genes after copper accumulation in COMMD1-deficient dogs. 25053573

2015
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0149519
Disease: Chronic Persistent Hepatitis
Chronic Persistent Hepatitis 		0.300 Biomarker CTD_human Aberrant expression of copper associated genes after copper accumulation in COMMD1-deficient dogs. 25053573

2015
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0520463
Disease: Chronic active hepatitis
Chronic active hepatitis 		0.300 Biomarker CTD_human Aberrant expression of copper associated genes after copper accumulation in COMMD1-deficient dogs. 25053573

2015
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0524611
Disease: Cryptogenic Chronic Hepatitis
Cryptogenic Chronic Hepatitis 		0.300 Biomarker CTD_human Aberrant expression of copper associated genes after copper accumulation in COMMD1-deficient dogs. 25053573

2015
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0019054
Disease: Hemolysis (disorder)
Hemolysis (disorder) 		0.300 Biomarker CTD_human Haemolysis and perturbations in the systemic iron metabolism of suckling, copper-deficient mosaic mutant mice - an animal model of Menkes disease. 25247420

2014
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0020542
Disease: Pulmonary Hypertension
Pulmonary Hypertension 		0.300 Biomarker CTD_human In summary, the data from this study indicate that increased Cu transportation due to upregulated CTR1 and ATP7A in pulmonary arteries and PASMC contributes to the development of hypoxia-induced pulmonary hypertension. 24614111

2014
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0235574
Disease: Intravascular hemolysis
Intravascular hemolysis 		0.300 Biomarker CTD_human Haemolysis and perturbations in the systemic iron metabolism of suckling, copper-deficient mosaic mutant mice - an animal model of Menkes disease. 25247420

2014
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0312854
Disease: Extravascular Hemolysis
Extravascular Hemolysis 		0.300 Biomarker CTD_human Haemolysis and perturbations in the systemic iron metabolism of suckling, copper-deficient mosaic mutant mice - an animal model of Menkes disease. 25247420

2014
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0002871
Disease: Anemia
Anemia 		0.300 Biomarker CTD_human Investigation of iron metabolism in mice expressing a mutant Menke's copper transporting ATPase (Atp7a) protein with diminished activity (Brindled; Mo (Br) (/y) ). 23776592

2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0019207
Disease: Hepatoma, Morris
Hepatoma, Morris 		0.300 Biomarker CTD_human Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. 23792645

2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0019208
Disease: Hepatoma, Novikoff
Hepatoma, Novikoff 		0.300 Biomarker CTD_human Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. 23792645

2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0023904
Disease: Liver Neoplasms, Experimental
Liver Neoplasms, Experimental 		0.300 Biomarker CTD_human Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. 23792645

2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0086404
Disease: Experimental Hepatoma
Experimental Hepatoma 		0.300 Biomarker CTD_human Non-hepatic tumors change the activity of genes encoding copper trafficking proteins in the liver. 23792645

2013
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0004134
Disease: Ataxia
Ataxia 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0018273
Disease: Growth Disorders
Growth Disorders 		0.300 Biomarker CTD_human Maternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein. 23064757

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0022333
Disease: Jacksonian Seizure
Jacksonian Seizure 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0027854
Disease: Neurologic Manifestations
Neurologic Manifestations 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0027854
Disease: Neurologic Manifestations
Neurologic Manifestations 		0.300 Biomarker CTD_human Maternofetal and neonatal copper requirements revealed by enterocyte-specific deletion of the Menkes disease protein. 23064757

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0040822
Disease: Tremor
Tremor 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0040827
Disease: Saturnine Tremor
Saturnine Tremor 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0149840
Disease: Senile Tremor
Senile Tremor 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0234370
Disease: Persistent Tremor
Persistent Tremor 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012
Entrez Id: 538
Gene Symbol: ATP7A
ATP7A
CUI: C0234371
Disease: Continuous Tremor
Continuous Tremor 		0.300 Biomarker CTD_human Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). 22815746

2012