Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54106
Gene Symbol: TLR9
TLR9
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.010 GeneticVariation BEFREE <b>Methods</b>: The Therapeutic Advances in Childhood Leukemia and Lymphoma Phase I consortium performed a pilot study on 3 patients with MRD positive acute leukemia after an initial remission on conventional chemotherapy (TACL T2009-008) with the TLR 9 agonist (GNKG168). 31530240

2019

Entrez Id: 6687
Gene Symbol: SPG7
SPG7
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 10206
Gene Symbol: TRIM13
TRIM13
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 653108
Gene Symbol: CXADRP1
CXADRP1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 1525
Gene Symbol: CXADR
CXADR
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 846
Gene Symbol: CASR
CASR
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 407
Gene Symbol: ARR3
ARR3
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.020 GeneticVariation BEFREE <i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)-Current Treatment Options. Is There a Role for CAR-T Cell Therapy? 31671855

2019

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.030 AlteredExpression BEFREE (2) HLA typing and MLC testing of all four family members revealed sharing of HLA-A,D and DRw determinants between the parents and pointed to the appearance of suppressor cell activity with the outbreak of the acute leukemia of one sibling. 6453845

1980

Entrez Id: 6343
Gene Symbol: SCT
SCT
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.030 Biomarker BEFREE 577 patients with acute leukemia or myelodysplastic syndrome receiving haplo-SCT were enrolled in the study. 29155367

2018

Entrez Id: 2120
Gene Symbol: ETV6
ETV6
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin. 20589932

2010

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemia in early age (EAL) is characterized by acquired genetic alterations such as MLL rearrangements (MLL-r). 24564228

2014

Entrez Id: 947
Gene Symbol: CD34
CD34
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 Biomarker BEFREE Acute leukemia expressing the normal human hematopoietic stem cell membrane glycoprotein CD34 (MY10). 2459568

1988

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemias with KMT2A rearrangements have different prognoses, which depend on the partner gene involved in the translocation. 25892123

2015

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemias (AL) with a Mixed Lineage Leukemia (MLL) gene rearrangement (MLLr) represent a group of leukemic entities conferring intermediate to adverse prognoses. 30446944

2019

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemias harboring KMT2A/MLLT10 fusion: a 10-year experience from a single genomics laboratory. 30707474

2019

Entrez Id: 952
Gene Symbol: CD38
CD38
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.090 GeneticVariation BEFREE Acute leukemia with t(10;11)(p11-p15;q13-q23). 8616782

1996

Entrez Id: 2125
Gene Symbol: EVPL
EVPL
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.010 AlteredExpression BEFREE Acute leukemias expressing p210-and p 190-type bcr/abl mRNAs: report of two cases and review of the literature. 8701709

1996

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE Acute leukemia with t(4;11)(q21,q23) translocation results from the in-frame fusion of the MLL to the AF4/FEL gene. 9808577

1998

Entrez Id: 4299
Gene Symbol: AFF1
AFF1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.060 GeneticVariation BEFREE Acute leukemia with t(4;11)(q21,q23) translocation results from the in-frame fusion of the MLL to the AF4/FEL gene. 9808577

1998

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 Biomarker BEFREE MLL-AF1q fusion resulting from t(1;11) in acute leukemia. 10025907

1999

Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.090 Biomarker BEFREE CD117 should be included on a routine basis for the immunophenotypic diagnosis of acute leukemias. 10229319

1999

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 GeneticVariation BEFREE MLL gene rearrangements identify a subgroup of acute leukemias with a bad prognosis. 10374852

1999

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.100 AlteredExpression BEFREE MDR1/P-GP expression as a prognostic factor in acute leukemias. 10500774

1999