Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.400 Biomarker CTD_human STAT-3 is active during the regenerative growth of the liver, but there are hardly any data about its presence in liver tumours. 12957465

2003

Entrez Id: 5357
Gene Symbol: PLS1
PLS1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 22996
Gene Symbol: TTC39A
TTC39A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 7358
Gene Symbol: UGDH
UGDH
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 128439
Gene Symbol: SNHG11
SNHG11
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 3697
Gene Symbol: ITIH1
ITIH1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.340 Biomarker CTD_human A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression. 16391232

2006

Entrez Id: 2705
Gene Symbol: GJB1
GJB1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.370 Biomarker CTD_human A rat liver gap junction (GJ) cDNA probe that detects mRNA encoding the 32 Kd GJ-protein (connexin 32) was employed to study GJ-protein gene expression in rat liver tumors induced by a single exposure to diethylnitrosamine (DEN) followed by exposure to 2-acetylaminofluorene (AAF)/CCl4/AAF or induced by systemic administration of N-ethyl-N-hydroxyethylnitrosamine (EHEN). 2559087

1989

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.700 Biomarker CTD_human Abnormalities of the ARF-p53 pathway in primary angiosarcomas of the liver. 12378512

2002

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.690 Biomarker CTD_human Abnormalities of the ARF-p53 pathway in primary angiosarcomas of the liver. 12378512

2002

Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.370 Biomarker CTD_human Activation of Nrf2 by microcystin-LR provides advantages for liver cancer cell growth. 20722399

2010

Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.510 Biomarker CTD_human Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. 12112319

2002

Entrez Id: 3054
Gene Symbol: HCFC1
HCFC1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.310 Biomarker CTD_human BR males are also moderately susceptible, and the susceptibility of both sexes of BR mice to liver tumors induced with N,N-diethylnitrosamine relative to the resistant C57BL/6J (B6) strain is caused by two loci designated Hcf1 and Hcf2 (hepatocarcinogenesis in females) located on chromosomes 17 and 1, respectively. 19255062

2009

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.400 Biomarker CTD_human Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan. 24183702

2014

Entrez Id: 3725
Gene Symbol: JUN
JUN
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.320 Biomarker CTD_human Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan. 24183702

2014

Entrez Id: 30061
Gene Symbol: SLC40A1
SLC40A1
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver. 21785164

2011

Entrez Id: 1437
Gene Symbol: CSF2
CSF2
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.360 Therapeutic CTD_human Combination therapy with GM-CSF and IL-12 represents a promising immunotherapy strategy for treating orthotopic, widespread liver tumors. 17326190

2007

Entrez Id: 3593
Gene Symbol: IL12B
IL12B
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Therapeutic CTD_human Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors. 17326190

2007

Entrez Id: 3592
Gene Symbol: IL12A
IL12A
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Therapeutic CTD_human Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors. 17326190

2007

Entrez Id: 196
Gene Symbol: AHR
AHR
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.400 Biomarker CTD_human Constitutive Activation of the Human Aryl Hydrocarbon Receptor in Mice Promotes Hepatocarcinogenesis Independent of Its Coactivator Gadd45b. 30346592

2019

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.370 Biomarker CTD_human Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene. 12127263

2002

Entrez Id: 3725
Gene Symbol: JUN
JUN
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.320 Biomarker CTD_human Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene. 12127263

2002

Entrez Id: 3856
Gene Symbol: KRT8
KRT8
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.310 Biomarker CTD_human Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions. 19796649

2010

Entrez Id: 3875
Gene Symbol: KRT18
KRT18
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.300 Biomarker CTD_human Cytokeratin 8/18 as a new marker of mouse liver preneoplastic lesions. 19796649

2010

Entrez Id: 3856
Gene Symbol: KRT8
KRT8
CUI: C0023903
Disease: Liver neoplasms
Liver neoplasms
0.310 Biomarker CTD_human Cytokeratin 8/18 overexpression and complex formation as an indicator of GST-P positive foci transformation into hepatocellular carcinomas. 19409407

2009