Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 613
Gene Symbol: BCR
BCR
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.500 Biomarker BEFREE Two male patients with myeloproliferative disorders (osteomyelosclerosis in one and CML in the other) were found to have a chromosomal marker 20q- in blood cells (unstimulated short time cultures). 288724

1979

Entrez Id: 2990
Gene Symbol: GUSB
GUSB
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Evidence for gene dosage effect for beta-glucuronidase (GUSB) and phosphoserine phosphatase (PSP), whose genes are mapped on chromosome 7, was searched in a group of 13 patients with myeloproliferative disorders and acquired monosomy 7. 1964582

1990

Entrez Id: 3976
Gene Symbol: LIF
LIF
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE The location of the LIF gene indicates that translocations of this gene are unlikely to play a role in myeloid leukemia and myeloproliferative disorders. 2491897

1989

Entrez Id: 3251
Gene Symbol: HPRT1
HPRT1
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE X-chromosome DNA probes for the phosphoglycerate kinase (PGK) and hypoxanthine phosphoribosyl transferase (HPRT) genes were used to study clonality in haemopoietic cells from 63 women with myeloproliferative disease, idiopathic erythrocytosis, secondary erythrocytosis or normal red cell volumes. 2775657

1989

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.050 Biomarker BEFREE Analysis of her erythroid progenitors showed the presence of erythropoietin-independent progenitors before, during, and after her pregnancy, consistent with a diagnosis of myeloproliferative disease, and persistence of the abnormal clone throughout the period of study. 2898487

1988

Entrez Id: 613
Gene Symbol: BCR
BCR
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.500 Biomarker BEFREE We have reviewed literature data on 6,306 cases of hematological neoplasia--acute and chronic lymphatic and myeloid leukemias (CML excepted), myelodysplastic and chronic lymphoproliferative and myeloproliferative disorders, and malignant lymphomas--with the goal of quantitatively ascertaining how often cytogenetically unrelated clones occur in these diseases. 2909809

1989

Entrez Id: 3040
Gene Symbol: HBA2
HBA2
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 AlteredExpression BEFREE The loss of alpha-globin gene transcriptional activity rarely occurs as an acquired abnormality during the evolution of myeloproliferative disease or preleukemia. 3031681

1987

Entrez Id: 3039
Gene Symbol: HBA1
HBA1
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 AlteredExpression BEFREE The loss of alpha-globin gene transcriptional activity rarely occurs as an acquired abnormality during the evolution of myeloproliferative disease or preleukemia. 3031681

1987

Entrez Id: 5327
Gene Symbol: PLAT
PLAT
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE The t-PA gene localization coincides with a translocation breakpoint observed in myeloproliferative disorders. 3092643

1986

Entrez Id: 2187
Gene Symbol: FANCB
FANCB
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.020 GeneticVariation BEFREE Two further cases with myeloproliferative disorders (a child with smoldering leukemia and a young male with acute nonlymphocytic leukemia of FAB type M2) and a translocation t(6;9)(p23;q34) are described. 3567880

1987

Entrez Id: 2539
Gene Symbol: G6PD
G6PD
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE The origin and nature of cells forming the in vitro microenvironment in long-term cultures of human marrow were studied in five patients with clonal myeloproliferative disorders who were heterozygous for glucose-6-phosphatase dehydrogenase (G6PD). 6471898

1984

Entrez Id: 2538
Gene Symbol: G6PC
G6PC
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE The origin and nature of cells forming the in vitro microenvironment in long-term cultures of human marrow were studied in five patients with clonal myeloproliferative disorders who were heterozygous for glucose-6-phosphatase dehydrogenase (G6PD). 6471898

1984

Entrez Id: 3562
Gene Symbol: IL3
IL3
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.050 Biomarker BEFREE The effect of mast cell growth factor on peripheral blood granulocyte-macrophage colony-forming cells in methylcellulose in myeloproliferative disorders. 7589339

1995

Entrez Id: 4254
Gene Symbol: KITLG
KITLG
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.020 Biomarker BEFREE The effect of mast cell growth factor on peripheral blood granulocyte-macrophage colony-forming cells in methylcellulose in myeloproliferative disorders. 7589339

1995

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.020 GeneticVariation BEFREE A novel t(9;11)(p22;q23) with ALL-1 gene rearrangement associated with progression of a myeloproliferative disorder to acute myeloid leukemia. 7656208

1995

Entrez Id: 100310785
Gene Symbol: ALL1
ALL1
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE A novel t(9;11)(p22;q23) with ALL-1 gene rearrangement associated with progression of a myeloproliferative disorder to acute myeloid leukemia. 7656208

1995

Entrez Id: 2120
Gene Symbol: ETV6
ETV6
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.100 GeneticVariation BEFREE Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. 7731705

1995

Entrez Id: 4330
Gene Symbol: MN1
MN1
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Translocation (12;22) (p13;q11) in myeloproliferative disorders results in fusion of the ETS-like TEL gene on 12p13 to the MN1 gene on 22q11. 7731705

1995

Entrez Id: 613
Gene Symbol: BCR
BCR
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.500 Biomarker BEFREE An unusual cytogenetic translocation, t(8;13) (p11;q12), is described in a patient presenting with a CML-like myeloproliferative disorder associated with a high-grade T-cell lymphoma. 7918088

1994

Entrez Id: 796
Gene Symbol: CALCA
CALCA
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 GeneticVariation BEFREE In this work the methylation status of the 5' area of the calcitonin gene in myeloproliferative disorders (MPD) other than chronic myeloid leukemia (CML) is studied. 8309247

1994

Entrez Id: 239
Gene Symbol: ALOX12
ALOX12
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Decreased messenger RNA of arachidonate 12-lipoxygenase in platelets of patients with myeloproliferative disorders. 8422429

1993

Entrez Id: 4352
Gene Symbol: MPL
MPL
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.500 Biomarker BEFREE Proto-oncogene c-mpl is involved in spontaneous megakaryocytopoiesis in myeloproliferative disorders. 8562412

1996

Entrez Id: 1161
Gene Symbol: ERCC8
ERCC8
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Spontaneous megakaryocytic colonies (CFU-MK) formation without the addition of Meg-CSA in myeloproliferative disorders (MPD) has been reported by many laboratories. 8562412

1996

Entrez Id: 1442
Gene Symbol: CSH1
CSH1
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Spontaneous megakaryocytic colonies (CFU-MK) formation without the addition of Meg-CSA in myeloproliferative disorders (MPD) has been reported by many laboratories. 8562412

1996

Entrez Id: 1443
Gene Symbol: CSH2
CSH2
CUI: C0027022
Disease: Myeloproliferative disease
Myeloproliferative disease
0.010 Biomarker BEFREE Spontaneous megakaryocytic colonies (CFU-MK) formation without the addition of Meg-CSA in myeloproliferative disorders (MPD) has been reported by many laboratories. 8562412

1996