×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
BRCA1 sequence analysis in women at high risk for susceptibility mutations. Risk factor analysis and implications for genetic testing.
9333265
1997
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Assessment of functional effects of unclassified genetic variants.
18951449
2008
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.
17924331
2007
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes.
21702907
2011
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
The role of targeted BRCA1/BRCA2 mutation analysis in hereditary breast/ovarian cancer families of Portuguese ancestry.
24916970
2015
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
A comprehensive functional characterization of BRCA2 variants associated with Fanconi anemia using mouse ES cell-based assay.
21719596
2011
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Two Missense Mutations in the Primary Autosomal Recessive Microcephaly Gene MCPH1 Disrupt the Function of the Highly Conserved N-Terminal BRCT Domain of Microcephalin.
22855649
2012
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO).
22762150
2012
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Comprehensive mutational analysis of BRCA1/BRCA2 for Korean breast cancer patients: evidence of a founder mutation.
19656164
2009
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
A large deletion disrupts the exon 3 transcription activation domain of the BRCA2 gene in a breast/ovarian cancer family.
9537232
1998
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Sensitivity of BRCA1/2 testing in high-risk breast/ovarian/male breast cancer families: little contribution of comprehensive RNA/NGS panel testing.
27273131
2016
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families.
9609997
1998
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Variation in breast cancer risk associated with factors related to pregnancies according to truncating mutation location, in the French National BRCA1 and BRCA2 mutations carrier cohort (GENEPSO).
22762150
2012
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Identification of breast tumor mutations in BRCA1 that abolish its function in homologous DNA recombination.
20103620
2010
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Multimodel assessment of BRCA1 mutations in Taiwanese (ethnic Chinese) women with early-onset, bilateral or familial breast cancer.
22277901
2012
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Germline mutations in BRCA1 and BRCA2 in epithelial ovarian cancer patients in Brazil.
27914478
2016
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Thermal unfolding of human BRCA1 BRCT-domain variants.
17493881
2007
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
The BRCA1 C-terminal domain: structure and function.
10946236
2000
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Cancer variation associated with the position of the mutation in the BRCA2 gene.
15131399
2004
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
27433846
2016
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Functional Assessment of Genetic Variants with Outcomes Adapted to Clinical Decision-Making.
27272900
2016
×
Entrez Id:
672
Gene Symbol:
BRCA1
BRCA1
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
LOVD v.2.0: the next generation in gene variant databases.
21520333
2011
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Novel germline mutations in BRCA2 gene among breast and breast-ovarian cancer families from Poland.
20383589
2010
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Evaluation of a 5-tier scheme proposed for classification of sequence variants using bioinformatic and splicing assay data: inter-reviewer variability and promotion of minimum reporting guidelines.
23893897
2013
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
Hereditary Breast and Ovarian Cancer Syndrome
0.800
GeneticVariation
CLINVAR
Detection of BRCA1 and BRCA2 mutations in breast cancer families by a comprehensive two-stage screening procedure.
10699917
2000