Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23140
Gene Symbol: ZZEF1
ZZEF1
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. 28566273

2017

Entrez Id: 23140
Gene Symbol: ZZEF1
ZZEF1
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018

Entrez Id: 23140
Gene Symbol: ZZEF1
ZZEF1
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. 29632382

2018

Entrez Id: 23140
Gene Symbol: ZZEF1
ZZEF1
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

Entrez Id: 140831
Gene Symbol: ZSWIM3
ZSWIM3
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASDB Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

Entrez Id: 7579
Gene Symbol: ZSCAN20
ZSCAN20
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain. 26629533

2015

Entrez Id: 84083
Gene Symbol: ZRANB3
ZRANB3
Diabetes Mellitus, Non-Insulin-Dependent
0.120 Biomarker BEFREE Genome-wide association studies in Africans have yielded genetic discovery that would otherwise not be possible; these include identification of novel loci associated with obesity (SEMA-4D, PRKCA, WARS2), metabolic syndrome (CA-10, CTNNA3), and T2D (AGMO, ZRANB3). 31520154

2019

Entrez Id: 84083
Gene Symbol: ZRANB3
ZRANB3
Diabetes Mellitus, Non-Insulin-Dependent
0.120 Biomarker BEFREE ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. 31324766

2019

Entrez Id: 84083
Gene Symbol: ZRANB3
ZRANB3
Diabetes Mellitus, Non-Insulin-Dependent
0.120 GeneticVariation GWASCAT ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. 31324766

2019

Entrez Id: 8882
Gene Symbol: ZPR1
ZPR1
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE In summary, these results suggest that ZPR1 plays an important role in the etiology of T2DM, and this gene might be involved in abnormal glucose metabolism. 27411854

2016

Entrez Id: 285971
Gene Symbol: ZNF775
ZNF775
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. 28736931

2018

Entrez Id: 130557
Gene Symbol: ZNF513
ZNF513
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker HPO

Entrez Id: 84627
Gene Symbol: ZNF469
ZNF469
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE Drug delivery and therapeutic challenges of gliclazide, a BCS class II drug used in type 2 diabetes mellitus (T2DM) can be overcome by exploring smarter carriers of second-generation nanocrystals (SGNCs). 31758056

2019

Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE Mitochondrial nt 3243 A-->G mutation was screened among 207 unrelated non-insulin-dependent diabetes mellitus (NIDDM) patients by using polymerase chain reaction (PCR)/Apa I restriction endonuclease digestion. 9594306

1997

Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
Diabetes Mellitus, Non-Insulin-Dependent
0.020 GeneticVariation BEFREE In CAD patients with type 2 diabetes mellitus (T2DM), Apa1showed a decreased risk in heterozygote model (OR = 0.80, 95% CI = 0.66-0.98); however, increased risk in recessive model (OR = 5.00, 95% CI = 2.74-9.13) was discovered in CAD patients without T2DM.The Fok1 polymorphism may play a protective role in CAD, and the possible protective role in Apa1 CA genotype in CAD patients with T2DM needs further studies. 27227912

2016

Entrez Id: 79797
Gene Symbol: ZNF408
ZNF408
Diabetes Mellitus, Non-Insulin-Dependent
0.100 Biomarker HPO

Entrez Id: 80778
Gene Symbol: ZNF34
ZNF34
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018

Entrez Id: 113835
Gene Symbol: ZNF257
ZNF257
Diabetes Mellitus, Non-Insulin-Dependent
0.400 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

Entrez Id: 113835
Gene Symbol: ZNF257
ZNF257
Diabetes Mellitus, Non-Insulin-Dependent
0.400 Biomarker CTD_human Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

Entrez Id: 8187
Gene Symbol: ZNF239
ZNF239
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE Nominally significant association (P<0.05) was observed for markers in: TCF7L2, RBMS1, CDKAL1, ZNF239, KCNQ1 and TCF1 and a significant bias (P<0.05) towards OR>1 was observed for markers selected from previous T2D genome-wide association studies, consistent with a role for Old World variants in susceptibility to T2D in Latin Americans. 22529894

2012

Entrez Id: 7776
Gene Symbol: ZNF236
ZNF236
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE Glucagon Levels During Short-Term SGLT2 Inhibition Are Largely Regulated by Glucose Changes in Patients With Type 2 Diabetes. 30137410

2019

Entrez Id: 94039
Gene Symbol: ZNF101
ZNF101
Diabetes Mellitus, Non-Insulin-Dependent
0.100 GeneticVariation GWASDB Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012

Entrez Id: 23613
Gene Symbol: ZMYND8
ZMYND8
Diabetes Mellitus, Non-Insulin-Dependent
0.010 Biomarker BEFREE This localization, combined with the observation that abnormalities in the activation, translocation, and inhibition of PKC occur in the development of Type II diabetes, suggested that PRKCBP1 was a candidate for contributing to Type II diabetes. 11003709

2000

Entrez Id: 10269
Gene Symbol: ZMPSTE24
ZMPSTE24
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE Clinically relevant ZMPSTE24 variants identified in the largest database of exomes sequences derived from T2D patients were characterized using the yeast model, revealing 14 partial loss-of-function variants, which were enriched among diabetes patients over 2-fold. 29526462

2018

Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
Diabetes Mellitus, Non-Insulin-Dependent
0.120 GeneticVariation GWASCAT Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. 31118516

2019