Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Multi-ethnic genome-wide association study identifies novel locus for type 2 diabetes susceptibility. 27189021

2016

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population. 19401414

2009

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. 17554300

2007

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Interaction of iron status with single nucleotide polymorphisms on incidence of type 2 diabetes. 28406950

2017

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association study identifies three novel loci for type 2 diabetes. 23945395

2014

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility. 25483131

2014

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT In addition to confirming two recently identified risk variants, we identified a variant in the CDKAL1 gene that was associated with T2D in individuals of European ancestry (allele-specific odds ratio (OR) = 1.20 (95% confidence interval, 1.13-1.27), P = 7.7 x 10(-9)) and individuals from Hong Kong of Han Chinese ancestry (OR = 1.25 (1.11-1.40), P = 0.00018). 17460697

2007

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. 22693455

2012

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. 17463246

2007

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population. 23575436

2013

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data. 19056611

2009

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. 20581827

2010

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls. 31118516

2019

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes. 29358691

2018

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. 19734900

2009

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations. 18711366

2008

Entrez Id: 54901
Gene Symbol: CDKAL1
CDKAL1
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. 18372903

2008