Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0000822
Disease: Abortion, Tubal
Abortion, Tubal 		0.300 Biomarker CTD_human Gene expression in cultured endometrium from women with different outcomes following IVF. 18539642

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0265287
Disease: Acromicric Dysplasia
Acromicric Dysplasia 		0.300 Biomarker CTD_human ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation. 18677313

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0751956
Disease: Acute Cerebrovascular Accidents
Acute Cerebrovascular Accidents 		0.300 Biomarker CTD_human A catalytic antioxidant (AEOL 10150) attenuates expression of inflammatory genes in stroke. 12374626

2002
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C2609414
Disease: Acute kidney injury
Acute kidney injury 		0.300 Biomarker CTD_human Kinetics of transforming growth factor-beta1 and extracellular matrix in renal tubulointerstitial lesions of mercuric chloride-treated Brown Norway rats. 10469268

1999
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1565662
Disease: Acute Kidney Insufficiency
Acute Kidney Insufficiency 		0.300 Biomarker CTD_human Kinetics of transforming growth factor-beta1 and extracellular matrix in renal tubulointerstitial lesions of mercuric chloride-treated Brown Norway rats. 10469268

1999
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury 		0.300 Biomarker CTD_human Gene expression changes during the development of acute lung injury: role of transforming growth factor beta. 16100012

2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma 		0.400 Therapeutic CTD_human Transforming growth factor beta-1 enhances cytotoxic effect of doxorubicin in human lung adenocarcinoma cells of A549 line. 17418594

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205641
Disease: Adenocarcinoma, Basal Cell
Adenocarcinoma, Basal Cell 		0.300 Therapeutic CTD_human Transforming growth factor beta-1 enhances cytotoxic effect of doxorubicin in human lung adenocarcinoma cells of A549 line. 17418594

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205642
Disease: Adenocarcinoma, Oxyphilic
Adenocarcinoma, Oxyphilic 		0.300 Therapeutic CTD_human Transforming growth factor beta-1 enhances cytotoxic effect of doxorubicin in human lung adenocarcinoma cells of A549 line. 17418594

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205645
Disease: Adenocarcinoma, Tubular
Adenocarcinoma, Tubular 		0.300 Therapeutic CTD_human Transforming growth factor beta-1 enhances cytotoxic effect of doxorubicin in human lung adenocarcinoma cells of A549 line. 17418594

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Biomarker CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544

2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		0.300 Biomarker CTD_human Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population. 19138248

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186

2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker CTD_human Protective effect of Gui Qi mixture on the progression of diabetic nephropathy in rats. 17177138

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Small interfering RNAs (siRNAs) targeting TGF-beta1 mRNA suppress asbestos-induced expression of TGF-beta1 and CTGF in fibroblasts. 19817698

2009
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Levels of cytokine in bronchoalveolar lavage (BAL) fluid in patients with pulmonary fibrosis due to sulfur mustard gas inhalation. 17266442

2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo. 24762191

2014
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice. 16324872

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Fibrogenic cytokine levels in bronchoalveolar lavage aspirates 15 years after exposure to sulfur mustard. 15286001

2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis. 26817844

2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C4721507
Disease: Alveolitis, Fibrosing
Alveolitis, Fibrosing 		0.300 Biomarker CTD_human NF-kappaB and activator protein 1 response elements and the role of histone modifications in IL-1beta-induced TGF-beta1 gene transcription. 16365456

2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0205696
Disease: Anaplastic carcinoma
Anaplastic carcinoma 		0.300 Therapeutic CTD_human Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. 12417722

2002
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0003504
Disease: Aortic Valve Insufficiency
Aortic Valve Insufficiency 		0.300 Biomarker CTD_human Usefulness of carvedilol in the treatment of chronic aortic valve regurgitation. 21216836

2011
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0004096
Disease: Asthma
Asthma 		0.700 Biomarker CTD_human Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population. 19138248

2008
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0004096
Disease: Asthma
Asthma 		0.700 Biomarker CTD_human Abnormal expression of TGF-beta1 is believed to play an important role in the pathogenesis of a number of chronic inflammatory and immune lung diseases, including asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis. 16365456

2006