×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Stathmin is involved in arsenic trioxide-induced apoptosis in human cervical cancer cell lines via PI3K linked signal pathway.
20657188 2010
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Activation of the PI3K /Akt pathway is associated with incomplete metabolic response in cervical cancer .
22235101 2012
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
AlteredExpression
BEFREE
Combination of valproic acid and ATRA restores RARβ2 expression and induces differentiation in cervical cancer through the PI3K /Akt pathway.
22229477 2012
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
These results suggest that targeted inhibition of PI3K /AKT may improve response to chemoradiation in cervical cancer .
23899375 2013
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Taken together, our data suggest that anti-VEGFa treatment in cervical cancer may inhibit both tumor cell growth and invasion through PI3k /Akt/mTor signaling pathway.
25135429 2014
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
CD38 was correlated with dysregulation of the phosphatidylinositol 3-kinase (PI3K )/Akt signaling pathway in cervical cancer tissues in vitro.
25310288 2014
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) protein is principally involved in the homeostatic maintenance of PI3K /Akt signaling and PTEN has been identified to play an important role in the occurrence and development of cervical cancer .
25738254 2015
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
AlteredExpression
BEFREE
Additionally, treatment with butein significantly increased reactive oxygen species (ROS) generation and reduced the phosphorylation of PI3K , AKT and mTOR expression, which contributes to the inhibition of the tumor growth of cervical cancer and reduction of oxidative stress.
25962638 2015
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
GeneticVariation
BEFREE
Here we demonstrate that PTEN destabilization is induced by EGFR- or oncogenic PI3K mutation-mediated AKT activation in cervical cancer .
26183061 2015
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Tumor-Suppressor Gene NBPF1 Inhibits Invasion and PI3K /mTOR Signaling in Cervical Cancer Cells.
26802646 2016
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
GeneticVariation
BEFREE
Seventy percent of patients with endometrial cancer and more than 50% of patients with breast, prostate, anal, hepatocellular, colorectal, and cervical cancer exhibited alterations in at least 1 PI3K pathway gene and/or gene product.
27388585 2016
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
The Potential Value of the PI3K /Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy.
28475243 2017
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Our study suggests that R7 is a promising chemotherapeutic agent for the treatment of cervical cancer and other PI3K /PTEN/Akt/mTOR signaling-associated tumors.
29312623 2017
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Aberrant activation of the phosphoinositide-3-kinase (PI3K ) pathway frequently occurs in solid tumors, including cervical cancer .
28036259 2017
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
MicroRNA‑433 inhibits cell growth and induces apoptosis in human cervical cancer through PI3K /AKT signaling by targeting FAK.
30272334 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Western blotting was utilized to validate whether NEAT1 promotes cervical cancer progression through activating PI3K -Akt signaling pathway.
30127216 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Fibulin-3 promoted cervical cancer cell invasive capabilities by eliciting EMT and activating the PI3K -Akt-mTOR signal transduction pathway.
30006571 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
microRNA-383 suppresses the PI3K -AKT-MTOR signaling pathway to inhibit development of cervical cancer via down-regulating PARP2.
29236322 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Baicalein inhibits cervical cancer progression via downregulating long noncoding RNA BDLNR and its downstream PI3K /Akt pathway.
29175387 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Tobacco Exposure Enhances Human Papillomavirus 16 Oncogene Expression via EGFR/PI3K /Akt/c-Jun Signaling Pathway in Cervical Cancer Cells.
30619121 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
let-7i-5p, miR-181a-2-3p and EGF/PI3K /SOX2 axis coordinate to maintain cancer stem cell population in cervical cancer .
29777148 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
miR-338 modulates proliferation and autophagy by PI3K /AKT/mTOR signaling pathway in cervical cancer .
29898430 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
GeneticVariation
BEFREE
Clinical outcomes and differential effects of PI3K pathway mutation in obese versus non-obese patients with cervical cancer .
29423104 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Here, we aimed to explore whether miR-486-5p is a regulator in the development of cervical cancer through the PI3K /Akt pathway by targeting PTEN.
29316891 2018
×
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
Malignant tumor of cervix
0.100
Biomarker
BEFREE
Knockdown of hnRNP A2/B1 inhibits cell proliferation, invasion and cell cycle triggering apoptosis in cervical cancer via PI3K /AKT signaling pathway.
29328485 2018