Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 56476
Gene Symbol: ABCB10P1
ABCB10P1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE A third of cooled children without CP had MABC-2 scores indicating motor impairment at school age that was not identified at 18 months by Bayley-III. 30883895

2019

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 GeneticVariation BEFREE Kinase domain (KD) mutations in the BCR-ABL gene are associated with resistance to imatinib in chronic myeloid leukemia (CML) but their incidence and prognostic significance in chronic phase (CP) patients without resistance are unclear. 18645191

2008

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 GeneticVariation BEFREE Among 208 CML patients, b3a2 BCR-ABL transcripts were most commonly detected (66.82%) followed by b2a2 (28.84%), b3a2 + b2a2 (3.36%), b3a2 + e19a2 (0.48%) and b2a2 + e19a2 (0.48%). b3a2 transcripts were more frequently detected than b2a2 transcripts, in the whole group of 208 as well as in 183 CML-CP patients (P<0.0001). 22382182

2012

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 AlteredExpression BEFREE As previously reported, BCR-ABL is downregulated during myeloid maturation in CP patients. 20520635

2010

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.040 Biomarker BEFREE Prior to the availability of long-term BCR-ABL inhibitor data, short-term surrogate end points predictive of longer-term outcomes have been identified using data from clinical trials of patients with CML-CP treated with interferon-α-based therapy and approved BCR-ABL inhibitors. 23383600

2013

Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE Compared to spinalis muscle from control patients with idiopathic scoliosis or cerebral palsy (CP), the patient with Escobar syndrome had a significantly higher degree of acetylcholine receptor present outside acetylcholinesterase and significantly less acetylcholinesterase outside acetylcholine receptors. 24038971

2013

Entrez Id: 116285
Gene Symbol: ACSM1
ACSM1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 GeneticVariation BEFREE The respondents were ten persons aged 22-56 with CP (MACS I-II). 31403825

2019

Entrez Id: 116285
Gene Symbol: ACSM1
ACSM1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.020 AlteredExpression BEFREE We tested 26 TC (mean age 9.5 ± 2.1 years) and 29 children with CP (age 9.6 ± 3 years) classified based on manual impairment levels as mild (Manual Ability Classification System [MACS] I; n = 18) or moderate-to-severe (MACS II-III, n = 11). 30138846

2018

Entrez Id: 123876
Gene Symbol: ACSM2A
ACSM2A
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE We tested 26 TC (mean age 9.5 ± 2.1 years) and 29 children with CP (age 9.6 ± 3 years) classified based on manual impairment levels as mild (Manual Ability Classification System [MACS] I; n = 18) or moderate-to-severe (MACS II-III, n = 11). 30138846

2018

Entrez Id: 111
Gene Symbol: ADCY5
ADCY5
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE In 23 patients molecular diagnosis was reached and included 5 hereditary spastic paraplegia genes (SPG) in spastic CP mimics; HPRT1, TH, QDPR, DDC in dystonic CP mimics; ADCY5 and NIKX2-1 in choreic CP mimics; CANA1A in ataxic CP mimics; and SPG, PDHA1, NIKX2-1, AT, SLC2A1 and SPR in mixed CP mimics. 30799092

2019

Entrez Id: 120
Gene Symbol: ADD3
ADD3
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.110 GeneticVariation BEFREE Mutations in γ adducin are associated with inherited cerebral palsy. 23836506

2013

Entrez Id: 120
Gene Symbol: ADD3
ADD3
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.110 CausalMutation CLINVAR

Entrez Id: 133
Gene Symbol: ADM
ADM
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE At a cut-off level of 30.6 ng/ml, the specificity of ADM to differentiate PDAC from controls and CP patients was 85.5 and 83.6%, with a sensitivity of 80 and 100%. 17290391

2007

Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE In white non-Hispanic children, beta-2 adrenergic receptor gln27glu was associated with CP risk; in Hispanic children, plasminogen activator inhibitor-1 (PAI-1) 4G(-675)5G and G11053T were associated with risk of CP. 15718364

2005

Entrez Id: 181
Gene Symbol: AGRP
AGRP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE The data that are available for malignancies seem reassuring, while results on neurodevelopmental health are more equivocal with a possible association between ART and cerebral palsy. 30753453

2019

Entrez Id: 199
Gene Symbol: AIF1
AIF1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.200 Biomarker RGD Developmental motor deficits induced by combined fetal exposure to lipopolysaccharide and early neonatal hypoxia/ischemia: a novel animal model for cerebral palsy in very premature infants. 19010395

2009

Entrez Id: 9049
Gene Symbol: AIP
AIP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.100 Biomarker HPO

Entrez Id: 213
Gene Symbol: ALB
ALB
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 AlteredExpression BEFREE We performed a nutritional assessment according to patterns of CP and determined 25-hydroxyvitaminD (25[OH]D) ferritin, and albumin levels. 29342407

2018

Entrez Id: 250
Gene Symbol: ALPP
ALPP
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE ALP (-46.64%), GGTase (-50.24%) and LAP (-42.15%), while NSO or TQ administration to CP treated rats significantly prevented the decline in the activities of these enzymes in isolated BBM vesicles (BBMVs) as well as in the homogenates of renal cortex and medulla. 29223554

2017

Entrez Id: 10717
Gene Symbol: AP4B1
AP4B1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker BEFREE Our results indicate that the 16 variants studied in the genes of the four subunits of AP-4 have no detectable effects on the overall susceptibility to CP, but AP4B1 appears to be a susceptibility gene for CP + HIE in the Han Chinese population. 24065543

2013

Entrez Id: 23431
Gene Symbol: AP4E1
AP4E1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 GeneticVariation BEFREE Interestingly, two mutations affecting AP4M1 and AP4E1 have recently been found to cause cerebral palsy associated with severe intellectual disability. 21620353

2011

Entrez Id: 9179
Gene Symbol: AP4M1
AP4M1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.130 GeneticVariation BEFREE A novel AP4M1 mutation in autosomal recessive cerebral palsy syndrome and clinical expansion of AP-4 deficiency. 25496299

2014

Entrez Id: 9179
Gene Symbol: AP4M1
AP4M1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.130 Biomarker HPO

Entrez Id: 9179
Gene Symbol: AP4M1
AP4M1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.130 GeneticVariation BEFREE Interestingly, two mutations affecting AP4M1 and AP4E1 have recently been found to cause cerebral palsy associated with severe intellectual disability. 21620353

2011

Entrez Id: 9179
Gene Symbol: AP4M1
AP4M1
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.130 GeneticVariation BEFREE Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy. 19559397

2009