Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE 1α,25(OH)<sub>2</sub>D<sub>3</sub> and MART-10, an analog of 1α,25(OH)<sub>2</sub>D<sub>3</sub>, effectively repressed VEGF-A-induced MCF-7 cell migration and invasion and other VEGF-A-induced effects on MCF-7 cells, with MART-10 being more potent than 1α,25(OH)<sub>2</sub>D<sub>3</sub> Conclusion: MART-10 can be deemed as a promising agent for prevention and treatment of metastasis of ER+ breast cancer with VEGF-A overexpression. 29970508

2018

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE 4-Acetylantroquinonol B suppresses tumor growth and metastasis of hepatoma cells via blockade of translation-dependent signaling pathway and VEGF production. 25494404

2015

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Metastases led to increased serum VEGF-A levels, indicating that VEGF-A may be involved in the growth of metastases. 20042655

2010

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Tumor cell migration is increased through the sequential induction of HIF-1α and VEGF under hypoxic conditions. 20878135

2010

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor-induced tumor angiogenesis and tumorigenicity in relation to metastasis in a HT1080 human fibrosarcoma cell model. 10048976

1999

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck. 10213212

1999

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that has a strong association with growth and metastasis of various cancers. 10772888

2000

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF), the most potent angiogenic factor identified to date, is associated with growth and metastasis of solid tumours, including melanoma. 10805219

2000

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is a potent angiogenic factor that promotes vascular growth and therefore tumoral growth and metastasis. 11232025

2001

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is a key angiogenic molecule that plays an important role in the growth and metastasis of many types of human cancer, including pancreatic adenocarcinoma. 11358838

2001

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is a potent angiogenic factor associated with the growth and metastasis of various cancers and plays a prominent role in vesical angiogenesis regulation. 11483411

2001

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 AlteredExpression BEFREE VEGF (vascular endothelial growth factor) expression was assessed against Nevin staging and metastasis of gallbladder carcinoma. 11584965

2001

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is one of the most important angiogenic factors involved in both tumor growth and metastasis. 12780519

2003

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is a potent angiogenic agent and plays a major role in tumor growth and metastases. 12855650

2003

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF), an angiogenic factor, plays a role in the growth, progression, and metastasis of solid tumors and it has been reported that VEGF expression is upregulated in cardiac myxomas that have a high microvessel density. 15118294

2004

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) promotes angiogenesis and is associated with the invasion and metastasis of malignant tumors. 16040218

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF, namely VEGF-A) is an angiogenic polypeptide and VEGF-C is a lymphangiogenic polypeptide that has been implicated in cancer growth, invasion and metastasis. 16109537

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 AlteredExpression BEFREE Vascular endothelial growth factor (VEGF) expression is elevated in primary ovarian tumors and metastases. 16152587

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is an essential peptide in new vessel growth in physiology (endometrial growth, embryonic development); pathological conditions (diabetic retinopathy, rheumatoid arthritis); as well as in tumor cell growth, particularly distant metastases. 16398617

2005

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 AlteredExpression BEFREE VEGF appears to be up-regulated in various cancers in which flt-1 may have a role in tumor progression and metastasis. 16432214

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) has been identified to be important in tumor angiogenesis, which is essential for the growth, invasion, and metastasis of solid tumors. 16525667

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF), a potent angiogenic factor, has been implicated in metastasis of colorectal cancer (CRC). 16600304

2006

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor plays a key role in human colorectal carcinoma invasion and metastasis. 17531111

2007

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF) is known as an important factor in the growth and metastasis of cancer cells. 17786959

2007

Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.400 Biomarker BEFREE Vascular endothelial growth factor (VEGF), one of the most potent angiogenic factors, is suggested to play a crucial role in tumor neovascularization and is associated with tumor progression and metastasis in prostate cancer. 17914566

2007