Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.900 GeneticVariation UNIPROT

Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.490 Biomarker CTD_human

Entrez Id: 4893
Gene Symbol: NRAS
NRAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.410 Biomarker CTD_human

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.350 Biomarker CTD_human

Entrez Id: 8313
Gene Symbol: AXIN2
AXIN2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human

Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human

Entrez Id: 201163
Gene Symbol: FLCN
FLCN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 6714
Gene Symbol: SRC
SRC
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 699
Gene Symbol: BUB1
BUB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 79695
Gene Symbol: GALNT12
GALNT12
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human

Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 10395
Gene Symbol: DLC1
DLC1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 2033
Gene Symbol: EP300
EP300
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human

Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids. 7705931

1995

Entrez Id: 5579
Gene Symbol: PRKCB
PRKCB
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Biomarker CTD_human Expression of protein kinase C isoenzymes in colorectal cancer tissue and their differential activation by different bile acids. 7705931

1995

Entrez Id: 3440
Gene Symbol: IFNA2
IFNA2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.300 Therapeutic CTD_human 5-Fluorouracil-interferon-alpha 2b adjuvant treatment of Dukes C colorectal cancer. 8026229

1994

Entrez Id: 999
Gene Symbol: CDH1
CDH1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.500 Biomarker CTD_human Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. 10072428

1999

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs. 10485483

1999

Entrez Id: 6648
Gene Symbol: SOD2
SOD2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.310 Biomarker CTD_human Overexpression of manganese superoxide dismutase mRNA may correlate with aggressiveness in gastric and colorectal adenocarcinomas. 10853026

2000

Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker CTD_human More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats. 10965019

2000

Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels. 11375891

2001

Entrez Id: 3481
Gene Symbol: IGF2
IGF2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.400 Biomarker CTD_human Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. 12637750

2003

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.700 Biomarker CTD_human Correlation of Ki-67, p53, and Adnab-9 immunohistochemical staining and ploidy with clinical and histopathologic features of severely dysplastic colorectal adenomas. 12645814

2003

Entrez Id: 4288
Gene Symbol: MKI67
MKI67
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.330 Biomarker CTD_human Correlation of Ki-67, p53, and Adnab-9 immunohistochemical staining and ploidy with clinical and histopathologic features of severely dysplastic colorectal adenomas. 12645814

2003

Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
0.380 Biomarker CTD_human The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype. 12690581

2003