×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
Bioinformatics analyses conducted on a Caucasian-based cDNA microarray databank showed Ar to be positively associated with GCa prognosis for multiple clinical modalities, including surgery, 5-Fluorouracil (5-FU) for adjuvant chemotherapy, or HER2 positivity.
31557413 2019
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
We recommend the number of tumor containing fragments be described in the HER2 IHC pathology reports for clinical reference in endoscopic biopsy specimens of GC .
28549444 2017
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
Advances in HER2 -Targeted Therapy: Novel Agents and Opportunities Beyond Breast and Gastric Cancer .
30442682 2019
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
PPP1R1B-STARD3-TCAP-PNMT-PERLD1-ERBB2 -MGC14832-GRB7 locus at human chromosome 17q12 is frequently amplified in human gastric cancer and breast cancer.
15010812 2004
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
Coamplified and overexpressed genes at ERBB2 locus in gastric cancer .
14991576 2004
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
Association analysis of ERBB2 amplicon genetic polymorphisms and STARD3 expression with risk of gastric cancer in the Chinese population.
24291029 2014
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
The SNPs rs2643194 , rs2934971 , and rs1058808 of the ERBB2 gene were associated with increased risk for GC .
31116314 2019
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
EBV-encoded RNA-positive cases were significantly associated with GC -MLI (P<.001), lower age (P=.016), diffuse/mixed type of histology (P=.011), and lower HER2 expression (P=.032).
27260946 2016
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
ERBB2 kinase domain mutation in a gastric cancer metastasis.16309427 2005
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
GeneticVariation
BEFREE
Prognostic implications of HER2 heterogeneity in gastric cancer .
29507688 2018
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
The expression of c-erbB-1 and c-erbB-2 in Iranian patients with gastric carcinoma .
12579211 2002
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Therefore, the present study aimed to elucidate the relationship between NPM and Her-2 in gastric cancer cell lines and clinical samples, and further investigated their role in the resistance of gastric cancer to oxaliplatin.
28454407 2017
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
How will human epidermal growth factor receptor 2 -neu data impact clinical management of gastric cancer ?
21505336 2011
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Classification of HER2 /neu status in gastric cancer using a breast-cancer derived proteome classifier.
21058730 2010
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
These data suggest that immuno-liposome mediated delivery of drugs is a promising new therapeutic option for patients with advanced gastric cancer that overexpress Her2 /neu.
21109923 2011
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
HER2 detection in mixed gastric carcinoma displays high heterogeneity.25914479 2015
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
However, the clinical significance of multi-targeting tyrosine kinase inhibitors (TKIs) in HER2 -positive gastric cancer remains unclear.
31704817 2019
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
c-erbB-2 oncogene has been reported to be frequently amplified in differentiated, tubular type of gastric cancer .
2575609 1989
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Gastric cancer (GC ) has also been slow to benefit from biomarker discovery and development and the successful utilisation of targeted therapies, with the exception of trastuzumab in HER2 positive cancers.30597479 2019
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
The anti-ErbB2 antibody trastuzumab has currently been approved for ErbB2 -positive gastric cancer .
24668364 2014
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Intratumoral heterogeneity of HER2 expression in the metastatic foci of HER2 -positive advanced gastric cancer remains unclear.
25828363 2015
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Consensus guidelines have standardized the testing of HER2 status in gastric cancer .
23021388 2013
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Patients with chemotherapy-naive HER2 -positive advanced gastric cancer were eligible.
26857702 2016
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Correlations between the expression levels of miR-21, PTEN, and p-AKT were analyzed by real-time PCR and Western blot test in HER2 -positive GC cell lines.
24154840 2014
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
Stomach Carcinoma
0.600
Biomarker
BEFREE
Clinical significance of intratumoral HER2 heterogeneity in gastric cancer .
23146959 2013