Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 29777
Gene Symbol: ABT1
ABT1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. 21364753

2011

Entrez Id: 27034
Gene Symbol: ACAD8
ACAD8
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. 21364753

2011

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.370 Biomarker CTD_human All three possible combinations of the ACE gene insertion/deletion polymorphism were found in gastric cancer cell lines, i.e., the DD- (AGS, MKN28), the II- (MKN45) and the ID-genotype (N87). 18059164

2007

Entrez Id: 70
Gene Symbol: ACTC1
ACTC1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009

Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101

2007

Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.340 Biomarker CTD_human Functional role of beta-adrenergic receptors in the mitogenic action of nicotine on gastric cancer cells. 17003101

2007

Entrez Id: 174
Gene Symbol: AFP
AFP
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker CTD_human Downregulation of AFP and STAT3 expression plays an important role in As(2)O(3)-induced apoptosis of AFPGC cells, which suggests a new mechanism of As(2)O(3)-induced cell apoptosis. 23382965

2013

Entrez Id: 186
Gene Symbol: AGTR2
AGTR2
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Expression of the local angiotensin II system in gastric cancer may facilitate lymphatic invasion and nodal spread. 18059164

2007

Entrez Id: 196
Gene Symbol: AHR
AHR
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.360 Biomarker CTD_human A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors. 12107286

2002

Entrez Id: 8644
Gene Symbol: AKR1C3
AKR1C3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.310 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009

Entrez Id: 213
Gene Symbol: ALB
ALB
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.400 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009

Entrez Id: 220
Gene Symbol: ALDH1A3
ALDH1A3
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer. 16367923

2006

Entrez Id: 501
Gene Symbol: ALDH7A1
ALDH7A1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. 21364753

2011

Entrez Id: 229
Gene Symbol: ALDOB
ALDOB
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009

Entrez Id: 240
Gene Symbol: ALOX5
ALOX5
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.310 Biomarker CTD_human Nicotine activated 5-lipoxygenase (5-LOX) in three gastric cancer cell lines (MKN-45, MKN-28 and AGS). 20061081

2010

Entrez Id: 308
Gene Symbol: ANXA5
ANXA5
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.310 Biomarker CTD_human Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer. 16367923

2006

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.700 Biomarker CTD_human

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.700 CausalMutation CGI

Entrez Id: 328
Gene Symbol: APEX1
APEX1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.380 Biomarker CTD_human A gene expression signature of acquired chemoresistance to cisplatin and fluorouracil combination chemotherapy in gastric cancer patients. 21364753

2011

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Diverse proteomic alterations in gastric adenocarcinoma. 15378696

2004

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.300 Biomarker CTD_human Two-dimensional differential in-gel electrophoresis for identification of gastric cancer-specific protein markers. 19424620

2009

Entrez Id: 374
Gene Symbol: AREG
AREG
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.360 Therapeutic CTD_human The findings reported here demonstrate that SN38 (the active metabolite of CPT-11) induces the tyrosine phosphorylation of EGFR within 5 min, followed by the induction of transcripts and/or proteins of the heparin-binding EGF-like growth factor, amphiregulin, transforming growth factor-alpha, and interlukin-8 (IL-8) in AGS gastric cancer cells. 15723263

2005

Entrez Id: 374
Gene Symbol: AREG
AREG
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.360 Biomarker CTD_human The findings reported here demonstrate that SN38 (the active metabolite of CPT-11) induces the tyrosine phosphorylation of EGFR within 5 min, followed by the induction of transcripts and/or proteins of the heparin-binding EGF-like growth factor, amphiregulin, transforming growth factor-alpha, and interlukin-8 (IL-8) in AGS gastric cancer cells. 15723263

2005

Entrez Id: 374
Gene Symbol: AREG
AREG
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.360 Therapeutic CTD_human Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer. 16367923

2006

Entrez Id: 374
Gene Symbol: AREG
AREG
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.360 Biomarker CTD_human Methylation status of the 32 randomly selected and 16 potential tumor-related genes was analyzed in 10 primary gastric cancers, and 42 genes (ABHD9, ADFP, ALDH1A3, ANXA5, AREG, BDNF, BMP7, CAV1, CDH2, CLDN3, CTSL, EEF1A2, F2R, FADS1, FSD1, FST, FYN, GPR54, GREM1, IGFBP3, IGFBP7, IRS2, KISS1, MARK1, MLF1, MSX1, MTSS1, NT5E, PAX6, PLAGL1, PLAU, PPIC, RBP4, RORA, SCRN1, TBX3, TFAP2C, TNFSF9, ULBP2, WIF1, ZNF177 and ZNF559) were methylated in at least one primary gastric cancer. 16367923

2006