Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human Serum proteomics of lung adenocarcinomas induced by targeted overexpression of c-raf in alveolar epithelium identifies candidate biomarkers. 17902193

2007

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human A 2-DE MALDI-TOF study to identify disease regulated serum proteins in lung cancer of c-myc transgenic mice. 19180532

2009

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human Varied pathways of stage IA lung adenocarcinomas discovered by integrated gene expression analysis. 21552421

2011

Entrez Id: 116285
Gene Symbol: ACSM1
ACSM1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays. 17114358

2007

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human The study identified and characterized three of these proteins, namely peroxiredoxin-6, β-actin and collagen α-1 (VI) as potentially prospective biomarkers for early detection of lung cancer. 23692979

2013

Entrez Id: 100
Gene Symbol: ADA
ADA
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.330 Biomarker CTD_human [Increase of the functional activity of natural killers under the effects of the pharmacological correction of the sympathoadrenal system state in patients with lung cancer]. 2305558

1990

Entrez Id: 10863
Gene Symbol: ADAM28
ADAM28
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human ADAM28: a potential oncogene involved in asbestos-related lung adenocarcinomas. 20544843

2010

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Therapeutic CTD_human Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1. 22619562

2012

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Therapeutic CTD_human Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 12511591

2003

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human Furthermore, aerosol delivery of GPT-SPE/Akt1 shRNA complexes significantly suppressed lung tumorigenesis in K-ras(LA1) lung cancer model mice. 21911043

2011

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. 12511591

2003

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human Suppression of lung cancer progression by biocompatible glycerol triacrylate-spermine-mediated delivery of shAkt1. 22619562

2012

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Therapeutic CTD_human Furthermore, aerosol delivery of GPT-SPE/Akt1 shRNA complexes significantly suppressed lung tumorigenesis in K-ras(LA1) lung cancer model mice. 21911043

2011

Entrez Id: 60529
Gene Symbol: ALX4
ALX4
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human ALX4 was readily expressed in normal lung tissues with an unmethylated status, but downregulated or silenced in 90% (9/10) of lung cancer cell lines with a hypermethylation status. 24037716

2014

Entrez Id: 288
Gene Symbol: ANK3
ANK3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017

Entrez Id: 253650
Gene Symbol: ANKRD18A
ANKRD18A
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human Moreover, weak expression of ANKRD18A in methylated lung cancer cell lines increased markedly after treatment with the DNA methylation inhibitor 5-aza-2'-deoxycytidine. 23131552

2012

Entrez Id: 302
Gene Symbol: ANXA2
ANXA2
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.360 Biomarker CTD_human The antibody titer against AnxA2 may be a potentially useful new diagnostic surrogate marker for asbestos-related lung cancer and malignant mesothelioma. 20682992

2010

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.400 Biomarker CTD_human DNA methylation markers and early recurrence in stage I lung cancer. 18337602

2008

Entrez Id: 335
Gene Symbol: APOA1
APOA1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human A 2-DE MALDI-TOF study to identify disease regulated serum proteins in lung cancer of c-myc transgenic mice. 19180532

2009

Entrez Id: 345
Gene Symbol: APOC3
APOC3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human A 2-DE MALDI-TOF study to identify disease regulated serum proteins in lung cancer of c-myc transgenic mice. 19180532

2009

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.350 Biomarker CTD_human A 2-DE MALDI-TOF study to identify disease regulated serum proteins in lung cancer of c-myc transgenic mice. 19180532

2009

Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.350 Biomarker CTD_human Apolipoprotein E expression promotes lung adenocarcinoma proliferation and migration and as a potential survival marker in lung cancer. 20430468

2011

Entrez Id: 60673
Gene Symbol: ATG101
ATG101
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017

Entrez Id: 475
Gene Symbol: ATOX1
ATOX1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.310 Biomarker CTD_human These findings suggest that ATOX1 plays an important role in copper-stimulated proliferation of NSCLC cells and ATOX1 holds potential as a therapeutic target for lung cancer therapy targeting copper metabolism. 23624903

2013

Entrez Id: 60370
Gene Symbol: AVPI1
AVPI1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung
0.300 Biomarker CTD_human Bronchial airway gene expression signatures in mouse lung squamous cell carcinoma and their modulation by cancer chemopreventive agents. 27935865

2017