×
Entrez Id:
1845
Gene Symbol:
DUSP3
DUSP3
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Taken together, these results suggest that PGG could be a potential therapeutic candidate for the treatment of cervical cancer through VHR inhibition.
31797547
2020
×
Entrez Id:
56970
Gene Symbol:
ATXN7L3
ATXN7L3
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
Enhanced expression of ATXN7L3 counterbalanced the DSCAM-AS1 knockdown effect on the progression of CC .
31737900
2020
×
Entrez Id:
4154
Gene Symbol:
MBNL1
MBNL1
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Based on sequencing data mining, we predicted that MBNL1 might be involved in the occurrence and poor prognosis of cervical cancer , and verifed that MBNL1 could regulate the resistance of HeLa cells to cisplatin via Nrf2.
31791583
2020
DSCAM-AS1
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
Enhanced expression of ATXN7L3 counterbalanced the DSCAM-AS1 knockdown effect on the progression of CC .
31737900
2020
×
Entrez Id:
5692
Gene Symbol:
PSMB4
PSMB4
Malignant tumor of cervix
0.010
Biomarker
BEFREE
In addition, the data analysis from TCGA showed a positive correlation between FxoM1 and PSMB4 in cervical cancer .
31699366
2020
×
Entrez Id:
693210
Gene Symbol:
MIR625
MIR625
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
Furthermore, the leucine-rich repeat containing the eight family member E (LRRC8E) could bind with miR-625 -5p, and its expression was negatively modulated by miR-625-5p, whereas positively regulated by LINC00958 in CC .
31691355
2020
×
Entrez Id:
51085
Gene Symbol:
MLXIPL
MLXIPL
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
Thus, we also explored whether TXNIP expression in cervical cancer can be regulated by MondoA or ChREBP .
31782782
2020
×
Entrez Id:
2498
Gene Symbol:
FTH1P3
FTH1P3
Malignant tumor of cervix
0.010
Biomarker
BEFREE
The present results demonstrated that lncRNA FTH1P3 functioned as a promoting factor in cervical cancer by targeting miR‑145.
31789421
2020
×
Entrez Id:
9263
Gene Symbol:
STK17A
STK17A
Malignant tumor of cervix
0.010
Biomarker
BEFREE
The overexpression of miR‑411 and low expression of STK17A were correlated with high efficacy of radiotherapy. miR‑411 and STK17A had predictive value for the efficacy of radiotherapy; miR‑411 was the protective factor and STK17A was a risk factor for prognosis of cervical cancer .
31746360
2020
×
Entrez Id:
80131
Gene Symbol:
LRRC8E
LRRC8E
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Final rescue assays verified the effects of LINC0095/LRRC8E interaction and miR-625-5p/LRRC8E interaction on CC cell proliferation and metastasis.
31691355
2020
×
Entrez Id:
3133
Gene Symbol:
HLA-E
HLA-E
Malignant tumor of cervix
0.010
Biomarker
BEFREE
This review aims to summarize and discuss the immunological role of HLA-E in the context of HPV infection and immune system evasion, and the oncogenic process of cervical cancer .
31733115
2020
TP73-AS1
Malignant tumor of cervix
0.010
Biomarker
BEFREE
TP73-AS1 might serve as a novel regulator in cervical cancer .
31232491
2020
×
Entrez Id:
100616469
Gene Symbol:
MIR4429
MIR4429
Malignant tumor of cervix
0.010
Biomarker
BEFREE
The current study tried to explore the role of miR-4429 in cell radio-sensitivity in CC .
31190335
2020
×
Entrez Id:
64285
Gene Symbol:
RHBDF1
RHBDF1
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
The results revealed that CC tissues had higher levels of iRhom1 and iRhom2 than adjacent normal tissues.
31661139
2020
×
Entrez Id:
205251
Gene Symbol:
MTLN
MTLN
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Our findings provide a foundation for understanding cervical cancer and facilitate the development of therapeutical approaches by targeting LINC00116 .
31693227
2020
×
Entrez Id:
154810
Gene Symbol:
AMOTL1
AMOTL1
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Our findings provide a better understanding of the molecular mechanism underlying circAMOTL1 in cervical cancer and indicated circAMOTL1/miR-485-5p/AMOTL1 as a promising novel therapeutic strategy for the treatment of this disease.
31812104
2020
×
Entrez Id:
442912
Gene Symbol:
MIR367
MIR367
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Our study highlights the involvement of miR-367 -3p/SPAG5/Wnt/β-catenin signaling axis in regulating the malignant progression of cervical cancer .
31792998
2020
×
Entrez Id:
79651
Gene Symbol:
RHBDF2
RHBDF2
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
The results revealed that CC tissues had higher levels of iRhom1 and iRhom2 than adjacent normal tissues.
31661139
2020
×
Entrez Id:
5606
Gene Symbol:
MAP2K3
MAP2K3
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Next, we demonstrated that over-expression of miR-214 or knockdown of MKK3 can inhibit the growth, proliferation, invasion and migration of cervical cancer in vitro and in vivo.
31634561
2020
×
Entrez Id:
375
Gene Symbol:
ARF1
ARF1
Malignant tumor of cervix
0.010
Biomarker
BEFREE
LncRNA TP73-AS1 is a novel regulator in cervical cancer via miR-329-3p/ARF1 axis.
31232491
2020
×
Entrez Id:
102723099
Gene Symbol:
GHET1
GHET1
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Rescue assays also proved that GHET1 regulated these two pathways and CC cell growth, migration and EMT through E2F6.
31682716
2020
×
Entrez Id:
100616326
Gene Symbol:
MIR4636
MIR4636
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Peripheral blood circulating microRNA-4636 /-143 for the prognosis of cervical cancer .
31407404
2020
×
Entrez Id:
26505
Gene Symbol:
CNNM3
CNNM3
Malignant tumor of cervix
0.010
Biomarker
BEFREE
For mechanism investigation, hsa_circ_0001038 could sponge miR-337-3p to release its suppression on cyclin-M3 (CNNM3 ) and metastasis-associated in colon cancer 1 (MACC1), thereby promoting CC cell growth and invasive potential, respectively.
31809842
2020
×
Entrez Id:
100886964
Gene Symbol:
PTCSC3
PTCSC3
Malignant tumor of cervix
0.010
Biomarker
BEFREE
Taken together, lncRNA PTCSC3 inhibited cell growth and metastasis via sponging miR-574-5p in cervical cancer .
31587336
2020
×
Entrez Id:
10628
Gene Symbol:
TXNIP
TXNIP
Malignant tumor of cervix
0.010
AlteredExpression
BEFREE
Thus, we also explored whether TXNIP expression in cervical cancer can be regulated by MondoA or ChREBP.
31782782
2020