Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 24
Gene Symbol: ABCA4
ABCA4
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE Upregulation of URI/RMP gene expression in cervical cancer by high-throughput tissue microarray analysis. 23573313

2013

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 Biomarker BEFREE Both ASPP and P-gp may be potential biomarkers in the treatment of cervical cancer. 31424649

2020

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 AlteredExpression BEFREE Collectively, these findings suggest that Twist1-mediated modulation of MDR1/P-gp expression plays an important role in sensitization of cervical cancer cells to cisplatin, and also indicate a novel therapeutic strategy to overcome drug resistance through inactivation of Twist1 expression in cervical cancer. 22245869

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 AlteredExpression BEFREE The mRNA expression levels of MDR1, LRP and GSTP1 in CC were 0.57±0.32, 0.58±0.29 and 0.44±0.24, respectively, whereas those in healthy cervical tissues were 0.19±0.10, 0.17±0.14 and 0.18±0.10, respectively. 28447725

2017

Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE This analysis exhibited frequent and robust upregulated expression in CC relative to normal cervix for genes EPHB2 (1p36), CDCA8 (1p34.3), AIM2 (1q22-23), RFC4, MUC4, and HRASLS (3q27-29), SKP2 (5p12-13), CENTD3 (5q31.3), PTK2, RECQL4 (8q24), MMP1 and MMP13 (11q22.2), AKT1 (14q32.3), ABCC3 (17q21-22), SMARCA4 (19p13.3) LIG1 (19q13.3), UBE2C (20q13.1), SMC1L1 (Xp11), KIF4A (Xq12), TMSNB (Xq22), and CSAG2 (Xq28). 17243165

2007

Entrez Id: 10257
Gene Symbol: ABCC4
ABCC4
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE We found that miR-506 was significantly downregulated in human CC cell lines (HeLa and C33A) and clinical CC specimens as compared with matched cell lines and adjacent normal tissues, while the expression level of ABCC4 was higher in tumor tissues than it in adjacent normal tissues. 29788724

2018

Entrez Id: 10061
Gene Symbol: ABCF2
ABCF2
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE Among cervical cancer cases, 149 (55.8%) expressed ABCF2. 19002184

2008

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE Both NOS1 and ABCG2 are important proliferation-promoting oncogenes in cervical cancer, which are expected to provide a certain theoretical basis for the treatment of cervical cancer. 30675209

2019

Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE SOX4 contributes to the progression of cervical cancer and the resistance to the chemotherapeutic drug through ABCG2. 26583330

2015

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker BEFREE Here we report that the Polo-like kinase PLK1, an essential mitotic kinase regulator, is an important downstream effector of c-ABL in regulating the growth of cervical cancer. c-ABL interacted with and phosphorylated PLK1. 27899378

2017

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker BEFREE Aqueous cinnamon extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential. 20482751

2010

Entrez Id: 57007
Gene Symbol: ACKR3
ACKR3
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker BEFREE However, the function and molecular mechanisms of action of CXCR7 in human cervical cancer are still unclear. 25422203

2014

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE Considering the relationship between the purinergic signaling and cancer, we studied the E-NTPDases, ecto-5'-nucleotidase, and E-NPPs in human cervical cancer cell lines and keratinocytes. 24697693

2014

Entrez Id: 55
Gene Symbol: ACP3
ACP3
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE It was further found that the level of knowledge on cervical cancer and PAP smear test was higher in the case group, which was more sensitive with regard to being informed about cervical cancer as compared to general society. 25684462

2015

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE GSEA analysis of cervical cancer specimens also showed that HPV16 E6 rather than HPV18 E6, was significantly associated with actin cytoskeleton assembly. 30230542

2019

Entrez Id: 60
Gene Symbol: ACTB
ACTB
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE A decrease in mtROS was found to induce formation of β-cytoplasmic actin stress fibers and circumferential rings in cervical cancer SiHa and Ca-Ski cells. 27902484

2017

Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 Biomarker BEFREE In the present study, we investigated the role of ACTN4 in regulating cancer cell stemness and chemoresistance in cervical cancer. 31584624

2019

Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 Biomarker BEFREE ACTN4 knockdown reduced cervical cancer cell proliferation and tumor formation in vivo. 27065319

2016

Entrez Id: 81
Gene Symbol: ACTN4
ACTN4
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.030 Biomarker BEFREE These findings demonstrate that NHERF1 inhibits Wnt signaling-mediated proliferation of cervical cancer via suppression of ACTN4, and NHERF1 downregulation may contribute to the progression of cervical cancer. 29867145

2018

Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE The TOP/ FOP-Flash reporter assay and Western blotting showed SOX17 inhibited the activity of the Wnt/β-catenin signaling pathway in cervical cancer. 29970906

2018

Entrez Id: 102
Gene Symbol: ADAM10
ADAM10
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker BEFREE Our study demonstrated that SNHG20 could function as an oncogenic lncRNA by regulating miR-140-5p-ADAM10 axis and MEK/ERK signaling pathway in cervical cancer. 29604594

2018

Entrez Id: 8754
Gene Symbol: ADAM9
ADAM9
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE The objective of this study was to investigate ADAM9 expression in cervical cancer and to determine the 31030477

2019

Entrez Id: 170692
Gene Symbol: ADAMTS18
ADAMTS18
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 Biomarker BEFREE Multivariate analysis demonstrated that ADAMTS18 was an independent prognostic factor for cervical cancer. 28362704

2018

Entrez Id: 103
Gene Symbol: ADAR
ADAR
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 AlteredExpression BEFREE ADAR1 overexpression is associated with cervical cancer progression and angiogenesis. 28109322

2017

Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.020 Biomarker BEFREE This fact suggest that ADCYAP1 can be used as an effective and sensitive methylation biomarker for the early diagnosis of cervical cancer. 21109983

2011