Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.320 Biomarker GENOMICS_ENGLAND

Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.300 Biomarker GENOMICS_ENGLAND

Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.300 Biomarker GENOMICS_ENGLAND

Entrez Id: 213
Gene Symbol: ALB
ALB
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 Biomarker BEFREE Diabetic nephropathy (defined as urinary albumin excretion greater than 300 mg/24 hr) was found in 7 out of 21 siblings to patients with nephropathy and 3 out of 30 siblings to normoalbuminuric patients (P less than 0.04). 1513092

1992

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Biomarker CTD_human L-dopa and streptozotocin-induced diabetic nephropathy in rats. 2143390

1990

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Therapeutic CTD_human L-dopa and streptozotocin-induced diabetic nephropathy in rats. 2143390

1990

Entrez Id: 213
Gene Symbol: ALB
ALB
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 Biomarker BEFREE In one set, the probands (n = 11) had no evidence of diabetic nephropathy, with normal creatinine clearance and a urinary albumin excretion rate below 45 mg per day. 2710189

1989

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Angiotensin-converting enzyme polymorphism and development of diabetic nephropathy in non-insulin-dependent diabetes mellitus. 7477652

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE It has been recently reported that in type 1 diabetes the insertion/deletion (I/D) polymorphism of the angiotensin I-converting enzyme gene is associated with the presence of diabetic nephropathy. 7485124

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Insertion/deletion polymorphism in the angiotensin-I-converting enzyme gene is associated with coronary heart disease in IDDM patients with diabetic nephropathy. 7556981

1995

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Biomarker CTD_human Selective proteinuria in diabetic nephropathy in the rat is associated with a relative decrease in glomerular basement membrane heparan sulphate. 7713310

1995

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Therapeutic CTD_human Selective proteinuria in diabetic nephropathy in the rat is associated with a relative decrease in glomerular basement membrane heparan sulphate. 7713310

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Lack of relationship between an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene and diabetic nephropathy and proliferative retinopathy in IDDM patients. 7729604

1995

Entrez Id: 5972
Gene Symbol: REN
REN
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.300 GeneticVariation BEFREE Genotypic abnormalities of the renin-angiotensin system have been suggested as a risk factor for the development of diabetic nephropathy and proliferative retinopathy. 7729604

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Association of ACE gene polymorphism and diabetic nephropathy? The Diabetic Nephropathy Study Group. 7783416

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Gene polymorphism for angiotensin converting enzyme is not linked to the development of microalbuminuria or established diabetic nephropathy. 7819935

1994

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.020 GeneticVariation BEFREE Our study was designed to elucidate whether the NAT2 gene polymorphism would be a marker for diabetic nephropathy. 7851073

1994

Entrez Id: 6046
Gene Symbol: BRD2
BRD2
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.010 GeneticVariation BEFREE The N-acetyltransferase (NAT) gene: an early risk marker for diabetic nephropathy in Japanese type 2 diabetic patients? 7851073

1994

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 Biomarker CTD_human Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene. 7909524

1994

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I--converting enzyme gene. 7909524

1994

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Therapeutic CTD_human Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats. 7987072

1994

Entrez Id: 3630
Gene Symbol: INS
INS
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.390 Biomarker CTD_human Glutathione status, lipid peroxidation and kidney function in streptozotocin diabetic rats. 7987072

1994

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE The II genotype of ACE gene is a marker for reduced risk for diabetic nephropathy. 8314010

1994

Entrez Id: 6678
Gene Symbol: SPARC
SPARC
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.220 Biomarker RGD SPARC gene expression is reduced in early diabetes-related kidney growth. 8569083

1995

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.600 GeneticVariation BEFREE Studies have shown an association of diabetic nephropathy and ischaemic heart disease with angiotensin converting enzyme gene polymorphism in subjects with diabetes. 8582133

1995