Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.900 CausalMutation CLINVAR

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.900 Biomarker MGD

Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.700 Biomarker HPO

Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.700 Biomarker CTD_human

Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.500 Biomarker HPO

Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.200 Biomarker HPO

Entrez Id: 3026
Gene Symbol: HABP2
HABP2
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.180 Biomarker HPO

Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.180 CausalMutation CLINVAR

Entrez Id: 23405
Gene Symbol: DICER1
DICER1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.140 Biomarker HPO

Entrez Id: 9562
Gene Symbol: MINPP1
MINPP1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 Biomarker HPO

Entrez Id: 182
Gene Symbol: JAG1
JAG1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 Biomarker HPO

Entrez Id: 3981
Gene Symbol: LIG4
LIG4
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 GeneticVariation CLINVAR

Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 CausalMutation CLINVAR

Entrez Id: 10483
Gene Symbol: SEC23B
SEC23B
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 Biomarker HPO

Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.600 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.600 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.600 Biomarker BEFREE Presence of aberrant transcripts of ret proto-oncogene in a human papillary thyroid carcinoma cell line. 2516841

1989

Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.400 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 2158
Gene Symbol: F9
F9
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 5726
Gene Symbol: TAS2R38
TAS2R38
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 7170
Gene Symbol: TPM3
TPM3
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.030 AlteredExpression BEFREE Since both PTC, a novel rearranged form of RET, and TRK display a tyrosine protein kinase activity, it is proposed that the activation of this class of oncogenes is specifically involved in the pathogenesis of papillary thyroid cancer. 2594368

1989

Entrez Id: 5979
Gene Symbol: RET
RET
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.600 Biomarker BEFREE The aberrant tyrosine kinase activity induced by the rearrangement of ret proto-oncogene could be involved in the development of papillary thyroid carcinoma. 2334411

1990

Entrez Id: 1956
Gene Symbol: EGFR
EGFR
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.100 AlteredExpression BEFREE We have found that TGF-alpha and EGF-R/c-erbB RNAs were co-expressed at significantly higher levels in papillary thyroid carcinomas and their lymph-node metastases than in non-neoplastic thyroid tissues. 1697567

1990