Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9830
Gene Symbol: TRIM14
TRIM14
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE In conclusion, TRIM14 may be a prognostic factor and oncogene in PTC, and may be a potential target for PTC intervention. 31668806

2020

Entrez Id: 10721
Gene Symbol: POLQ
POLQ
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE DNA polymerase theta expression by quantitative reverse-transcriptase Polymerase chain reaction was higher in papillary thyroid cancer and papillary thyroid cancer-adjacent samples than in benign normal thyroid (P < .001). 31439400

2020

Entrez Id: 2642
Gene Symbol: GCGR
GCGR
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE The Kaplan-Meier method was used to analyze the connection between GCGR expression and prognosis of PTC patients. 31782107

2020

Entrez Id: 285456
Gene Symbol: RPL34-AS1
RPL34-AS1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE The aim of this study was to investigate the effect of RPL34-AS1 in PTC and to explore its potential mechanisms. 31587286

2020

Entrez Id: 6666
Gene Symbol: SOX12
SOX12
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE Consequently, we found that NR2F1-AS1 and SOX12 levels were elevated in PTC, whereas miR-423-5p was downregulated in PTC cells. 31692033

2020

Entrez Id: 100302235
Gene Symbol: MIR1179
MIR1179
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Hsa_circ_0039411 promotes tumorigenesis and progression of papillary thyroid cancer by miR-1179/ABCA9 and miR-1205/MTA1 signaling pathways. 31270819

2020

Entrez Id: 693184
Gene Symbol: MIR599
MIR599
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE microRNA-599 promotes apoptosis and represses proliferation and epithelial-mesenchymal transition of papillary thyroid carcinoma cells via downregulation of Hey2-depentent Notch signaling pathway. 31565805

2020

Entrez Id: 406910
Gene Symbol: MIR125A
MIR125A
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Consistently, the colony formation ability and other metastasis-related traits of PTC cell are inhibited by miR-125a-3p transfection in vitro. 31489990

2020

Entrez Id: 4312
Gene Symbol: MMP1
MMP1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE This research retrospectively investigates the expression of MMP-1, -2 and -9 as well as TIMP-1 and -2 in papillary thyroid carcinoma tissue. 31646745

2020

Entrez Id: 406935
Gene Symbol: MIR143
MIR143
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Our results indicate that upregulation of miR-143-3p suppresses the progression of PTC by impeding cell growth, invasion, and migration via downregulation of MSI2, highlighting the potential of miR-143-3p as a target for future PTC treatment. 31738908

2020

Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE ATR-FTIR spectroscopy and CDKN1C gene expression in the prediction of lymph nodes metastases in papillary thyroid carcinoma. 31708464

2020

Entrez Id: 441094
Gene Symbol: NR2F1-AS1
NR2F1-AS1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE The impact of NR2F1-AS1 on PTC cell proliferation and invasion was assessed by Cell Counting Kit-8, EdU, and Transwell invasion assays. 31692033

2020

Entrez Id: 23642
Gene Symbol: SNHG1
SNHG1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Collectively, these findings unveil the potential regulation of SNHG1 on the PTC tumorigenesis via feedback loop, providing a novel insight for PTC. 31791587

2020

Entrez Id: 100302122
Gene Symbol: MIR1183
MIR1183
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE Data from Cell Counting Kit-8, colony formation assays and transwell assays revealed that the oncogenic role of circ_0005273 on PTC progression dependent on miR-1183-mediated SOX2 expression. 31693489

2020

Entrez Id: 100847057
Gene Symbol: MIR5189
MIR5189
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 GeneticVariation BEFREE AUC of 11 miRNAs was above 0.9, miR-5189-3p had the most optimal performance for diagnosis between PTC and NG, with 0.951 of AUC. 31560760

2020

Entrez Id: 100500893
Gene Symbol: MIR3663
MIR3663
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Moreover, RPL34-AS1 could also competitively bind miR-3663-3p and exert its function by regulating the miR-3663-3p/RGS4 in PTC cell lines. 31587286

2020

Entrez Id: 5999
Gene Symbol: RGS4
RGS4
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Moreover, RPL34-AS1 could also competitively bind miR-3663-3p and exert its function by regulating the miR-3663-3p/RGS4 in PTC cell lines. 31587286

2020

Entrez Id: 101927152
Gene Symbol: SAMMSON
SAMMSON
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Taken together, our data demonstrate that SAMMSON is an oncogenic lncRNA and unveil the crucial role of SAMMSON/Sp1 positive feedback loop in tumorigenesis and aggressiveness of PTC. 31478331

2020

Entrez Id: 7956
Gene Symbol: NTT
NTT
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE The pooled OR indicated that CXCR4 expression was significantly higher in PTC than that in normal thyroid tissue and benign thyroid nodule (NTT/BTN) (OR=67.22, 95% CI: 32.85-137.55, P < 0.00001). 29424203

2020

Entrez Id: 55364
Gene Symbol: IMPACT
IMPACT
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Impact factors for the outcome of the first <sup>131</sup>I radiotherapy in patients with papillary thyroid carcinoma after total thyroidectomy. 30515649

2019

Entrez Id: 693215
Gene Symbol: MIR630
MIR630
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE Overexpression of miR-630 inhibited PTC cell proliferation and induced cell apoptosis via suppressing the expression of caspase-3 and caspase-6. 30964171

2019

Entrez Id: 78990
Gene Symbol: OTUB2
OTUB2
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE Ectopic expression of OTUB2 can antagonize the effects of miR-29a-3p on cell growth, proliferation, and invasion of PTC. 30588107

2019

Entrez Id: 23481
Gene Symbol: PES1
PES1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE It is suggested that PES1 promotes the occurrence and development of PTC by elevating the ERα protein level and reducing the ERβ protein level, and then upregulating the ERα/ERβ protein ratio. 30705367

2019

Entrez Id: 152559
Gene Symbol: PAQR3
PAQR3
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 AlteredExpression BEFREE However, no study has investigated the expression of PAQR3 in papillary thyroid tissues in relation to the BRAF<sup>V600E</sup> mutation and the clinicopathological features of PTC patients. 31758408

2019

Entrez Id: 10454
Gene Symbol: TAB1
TAB1
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma
0.010 Biomarker BEFREE Moreover, TAB1 was shown to be a mediator for the roles of miR-758-3p in PTC. 30940308

2019