×
Entrez Id: 761
Gene Symbol: CA3
CA3
Chemically-Induced Liver Toxicity
0.500
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249 2015
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Chemically-Induced Liver Toxicity
0.500
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750 2011
×
Entrez Id: 6652
Gene Symbol: SORD
SORD
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity.
12763371 2003
×
Entrez Id: 100422867
Gene Symbol: MIR378C
MIR378C
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106 2017
×
Entrez Id: 574030
Gene Symbol: MIR362
MIR362
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106 2017
×
Entrez Id: 1356
Gene Symbol: CP
CP
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513 2014
×
Entrez Id: 2936
Gene Symbol: GSR
GSR
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Editor's Highlight: Transgenic Zebrafish Reporter Lines as Alternative In Vivo Organ Toxicity Models.
28069987 2017
×
Entrez Id: 406920
Gene Symbol: MIR130B
MIR130B
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
"Serum microRNA signatures as ""liquid biopsies"" for interrogating hepatotoxic mechanisms and liver pathogenesis in human."
28545106 2017
×
Entrez Id: 9970
Gene Symbol: NR1I3
NR1I3
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice.
28058446 2017
×
Entrez Id: 2936
Gene Symbol: GSR
GSR
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513 2014
×
Entrez Id: 8407
Gene Symbol: TAGLN2
TAGLN2
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513 2014
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750 2011
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Amiodarone exposure during modest inflammation induces idiosyncrasy-like liver injury in rats: role of tumor necrosis factor-alpha.
21984482 2012
×
Entrez Id: 383
Gene Symbol: ARG1
ARG1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
A performance evaluation of three drug-induced liver injury biomarkers in the rat: alpha-glutathione S-transferase, arginase 1, and 4-hydroxyphenyl-pyruvate dioxygenase.
22872058 2012
×
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism.
20709802 2010
×
Entrez Id: 4189
Gene Symbol: DNAJB9
DNAJB9
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
26881866 2016
×
Entrez Id: 60
Gene Symbol: ACTB
ACTB
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249 2015
×
Entrez Id: 7100
Gene Symbol: TLR5
TLR5
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
TLR5 silencing reduced hyperammonaemia-induced liver injury by inhibiting oxidative stress and inflammation responses via inactivating NF-κB and MAPK signals.
30508503 2019
×
Entrez Id: 9446
Gene Symbol: GSTO1
GSTO1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model.
25231249 2015
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome.
19164858 2009
×
Entrez Id: 3565
Gene Symbol: IL4
IL4
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.
21735453 2012
×
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis.
16770646 2006
×
Entrez Id: 4057
Gene Symbol: LTF
LTF
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration.
16141546 2005
×
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
Chemically-Induced Liver Toxicity
0.300
Therapeutic
CTD_human
Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity.
30393195 2019
×
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
Chemically-Induced Liver Toxicity
0.300
Biomarker
CTD_human
Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood.
20623750 2011