×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Adrenocortical carcinoma
0.800
GeneticVariation
UNIPROT
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Adrenocortical carcinoma
0.800
Biomarker
HPO
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Adrenocortical carcinoma
0.800
CausalMutation
CGI
×
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
Adrenocortical carcinoma
0.500
Biomarker
HPO
×
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
Adrenocortical carcinoma
0.420
Biomarker
HPO
×
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
Adrenocortical carcinoma
0.130
Biomarker
HPO
×
Entrez Id: 1028
Gene Symbol: CDKN1C
CDKN1C
Adrenocortical carcinoma
0.120
Biomarker
HPO
×
Entrez Id: 283120
Gene Symbol: H19
H19
Adrenocortical carcinoma
0.110
Biomarker
HPO
×
Entrez Id: 324
Gene Symbol: APC
APC
Adrenocortical carcinoma
0.110
Biomarker
HPO
×
Entrez Id: 3784
Gene Symbol: KCNQ1
KCNQ1
Adrenocortical carcinoma
0.100
Biomarker
HPO
KCNQ1OT1
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 105259599
Gene Symbol: H19-ICR
H19-ICR
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 1031
Gene Symbol: CDKN2C
CDKN2C
Adrenocortical carcinoma
0.100
Biomarker
HPO
×
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
Adrenocortical carcinoma
0.110
GeneticVariation
BEFREE
One patient with adrenocortical carcinoma had a somatic mutation in the HRAS1 gene in the normal adrenal gland.
2564050 1989
×
Entrez Id: 107648861
Gene Symbol: DEL11P13
DEL11P13
Adrenocortical carcinoma
0.010
GeneticVariation
BEFREE
Tumor-specific loss of 11p15.5 alleles in del11p13 Wilms tumor and in familial adrenocortical carcinoma .
2566168 1989
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Adrenocortical carcinoma
0.010
GeneticVariation
BEFREE
One patient with adrenocortical carcinoma had a somatic mutation in the HRAS1 gene in the normal adrenal gland.
2564050 1989
×
Entrez Id: 8045
Gene Symbol: RASSF7
RASSF7
Adrenocortical carcinoma
0.010
GeneticVariation
BEFREE
One patient with adrenocortical carcinoma had a somatic mutation in the HRAS1 gene in the normal adrenal gland.
2564050 1989
×
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
Adrenocortical carcinoma
0.330
Biomarker
BEFREE
The finding that multidrug resistance mediated by mdr-1 /Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer .
1675220 1991
×
Entrez Id: 23158
Gene Symbol: TBC1D9
TBC1D9
Adrenocortical carcinoma
0.020
Biomarker
BEFREE
The finding that multidrug resistance mediated by mdr-1 /Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer .
1675220 1991
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Adrenocortical carcinoma
0.800
GeneticVariation
BEFREE
Detection of novel germ-line p53 mutations in diverse-cancer-prone families identified by selecting patients with childhood adrenocortical carcinoma .
1569604 1992
×
Entrez Id: 324
Gene Symbol: APC
APC
Adrenocortical carcinoma
0.110
GeneticVariation
BEFREE
Loss of normal allele of the APC gene in an adrenocortical carcinoma from a patient with familial adenomatous polyposis.
1351034 1992
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Adrenocortical carcinoma
0.800
GeneticVariation
BEFREE
These data suggest that mutational inactivation of the p53 gene occurs in a minority (20%) of sporadic adrenocortical carcinomas and that these mutations constitute a late event in the multi-step process of malignant transformation.
8509216 1993