×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
Besides, CD44 variant isoform 6 (CD44v6), a protein marker for metastatic behavior in gastric cancer , and was chose as the target gene to further analyze the siRNA delivery function of PEG-g-PEI-SPION.
23179610
2013
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
CD44 -SLC1A2 gene fusions in gastric cancer .
21471434
2011
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
CD44E is a frequently overexpressed variant of CD44 in gastric cancer .
26119931
2016
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
Expression of CD44 variant exons 8-10 in gastric cancer .
8636005
1995
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
Haplotypes of OPN and CD44 variants significantly influenced risk of gastric cancer .
25009318
2014
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
The generation of CD44 splice variants might be linked closely with gastric carcinoma tumorigenesis and differentiation.
10439835
1999
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
CD44 single nucleotide polymorphism and isoform switching may predict gastric cancer recurrence.
26416034
2015
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
GeneticVariation
BEFREE
Expression and prognostic value of the CD44 splicing variants v5 and v6 in gastric cancer .
9390037
1997
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
This study aimed to conduct a meta-analysis on 19 lncRNAs (AFAP1 antisense RNA 1 [AFAP1-AS1], CDKN2B antisense RNA 1 [ANRIL], cancer susceptibility 15 [CASC15], colon cancer associated transcript 2 [CCAT2], gastric adenocarcinoma associated, positive CD44 regulator, long intergenic noncoding RNA [GAPLINC], H19, imprinted maternally expressed transcript [H19], HOX transcript antisense RNA [HOTAIR], HOXA distal transcript antisense RNA [HOTTIP], long intergenic non-protein coding RNA 673 [LINC00673], metastasis-associated lung adenocarcinoma transcript 1 [MALAT1], maternally expressed 3 [MEG3], promoter of CDKN1A antisense DNA damage activated RNA [PANDAR], Pvt1 oncogene [PVT1], SOX2 overlapping transcript [Sox2ot], SPRY4 intronic transcript 1 [SPRY4-IT1], urothelial cancer associated 1 [UCA1], X inactive specific transcript [XIST], ZEB1 antisense RNA 1 [ZEB1-AS1] and ZNFX1 antisense RNA 1 [ZFAS1]) to systematically estimate their prognostic value in GC .
30147339
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
Despite their suggested importance, the mechanistic roles of FGFR2 and gastric cancer stem cell (GCSC) marker CD44 remain unclear.
27107424
2016
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
This study was aimed to investigate the associations between single nucleotide polymorphisms of cancer stem cell marker genes, CD44 and CD133, and susceptibility and prognosis of gastric cancer .
28326835
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
Therefore, CD44 -SATB1-ILs represent an up-and-coming approach for eliminating gastric CICs and also a promising treatment for therapy of gastric cancer .
30349314
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
Circulating tumor cells expressing cancer stem cell marker CD44 as a diagnostic biomarker in patients with gastric cancer .
28123556
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
CD44 is a cell surface protein and it is widely used as a cancer stem cell marker in various cancer types including gastric cancer .
25081334
2014
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
The CD44 + gastric cancer cell model is a non-adhesion, 3-dimensional, spheroid phenotype.
23900519
2013
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
We recently identified miR-328 as one of the microRNAs targeting CD44 in gastric cancer .
25479940
2015
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
Cancer stem cell (CSC) with the mark of CD44 played an important role in GC . rMETase was wildly exploited as chemotherapeutic option for GC .
29858680
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
mtDNA depletion triggers chemoresistance in cancer cell lines and is correlated with increase and decrease of CD44 and CD24 positivity respectively in HGC-27 and MKN-45 GC cell lines.
29845783
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
miR-145 targeting of CD44 plays critical roles in the regulation of tumor growth and chemo-resistance in gastric cancer .
28428713
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
This study determined how 3D cultures impact CD44 alternative splicing in gastric cancer (GC ) cells.
27187279
2016
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
HOXA10(+)/CD44 (+) expression might serve as a prognostic biomarker for GC , which needs more studies to validate.
26552644
2015
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
In the first case, in a 73-year-old female, total gastrectomy was performed for a Gastric Cancer (GC ) that was proved to be, based on the immunohistochemical features (positivity for mammaglobin and estrogen receptor and negativity for E-cadherin, β-catenin, CD44 and maspin), a metastasis from an invasive lobular carcinoma of the breast, that was later confirmed.
29090670
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
A CD44 specific peptide developed by phage display for targeting gastric cancer .
26140900
2015
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
USP22-NLs-CD44 may provide a novel approach to eradicate gastric cancer stem cells in the near future.
30543303
2019
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
Stomach Carcinoma
0.100
Biomarker
BEFREE
In conclusion, results of the present study indicated that HDAC1 depletion inhibits the metastatic abilities of gastric cancer cells by regulating the miRNA-34a/CD44 pathway, which may be a potential target for the treatment of gastric cancer .
26035691
2015