Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 GeneticVariation BEFREE <b>Conclusion:</b> Our meta-analysis indicates that the <i>ALDH2</i> rs671 G>A polymorphism may play an important role in the occurrence of IS by reducing the activity of ALDH2 and interfering with the metabolic processes involving acetaldehyde. 31114208

2019

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 Biomarker BEFREE ALDH2(*)2 could be a protective factor and negative predictor for severe intracranial vascular stenosis in ischemic stroke in Han Chinese. 26000808

2016

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 GeneticVariation BEFREE Genetic variants in ALDH2 predict risk of ischemic stroke in a Chinese population. 30077765

2018

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 AlteredExpression BEFREE In conclusion, increasing ALDH2 activity can improve brain edema, infarct volumes, and reduce neurological impairment in a rat IS model. 29767275

2018

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 GeneticVariation GWASCAT Loci associated with ischaemic stroke and its subtypes (SiGN): a genome-wide association study. 26708676

2016

Entrez Id: 217
Gene Symbol: ALDH2
ALDH2
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.150 GeneticVariation BEFREE This study intended to further investigate whether the above variant of ALDH2 increases the risk for ischemic stroke in Taiwanese. 27486170

2016