Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.220 AlteredExpression BEFREE Antioxidant enzyme gene expression levels (Superoxide Dismutase-SOD1, SOD2, and SOD3) were increased and Tumor Necrosis Factor (TNF)α expression levels were decreased in the PC+PVL group when compared with the PVL group. 23063716

2012

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.220 GeneticVariation BEFREE Maternal and infant IL-10 (-1082, -819) and TNF-α (-308) genotypes are not indicative for an increased risk of preterm birth or the development of PVL in premature newborns. 21527907

2012

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.220 Biomarker RGD Consistent with reports that progenitor cells are preferentially injured in PVL, our results may further support the role of TNF-alpha as a potential mediator of PVL. 15765524

2005

Entrez Id: 4155
Gene Symbol: MBP
MBP
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.210 Biomarker BEFREE Myelination phenotype revealed by MBP immunostaining was not significantly affected in the p38α MAPK CKO mice compared to the wildtype after PVL induction. 29966722

2018

Entrez Id: 4155
Gene Symbol: MBP
MBP
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.210 Biomarker RGD Protective effects of pentoxifylline on lipopolysaccharide-induced white matter injury in a rat model of periventricular leukomalasia. 23614640

2013

Entrez Id: 54499
Gene Symbol: TMCO1
TMCO1
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 GeneticVariation CLINVAR

Entrez Id: 5091
Gene Symbol: PC
PC
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 57514
Gene Symbol: ARHGAP31
ARHGAP31
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 7167
Gene Symbol: TPI1
TPI1
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 CausalMutation CLINVAR

Entrez Id: 5373
Gene Symbol: PMM2
PMM2
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 GeneticVariation CLINVAR

Entrez Id: 3516
Gene Symbol: RBPJ
RBPJ
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 2961
Gene Symbol: GTF2E2
GTF2E2
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 26750
Gene Symbol: RPS6KC1
RPS6KC1
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 GeneticVariation CLINVAR

Entrez Id: 7737
Gene Symbol: RNF113A
RNF113A
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 GeneticVariation CLINVAR

Entrez Id: 6651
Gene Symbol: SON
SON
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 404672
Gene Symbol: GTF2H5
GTF2H5
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 2071
Gene Symbol: ERCC3
ERCC3
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 54567
Gene Symbol: DLL4
DLL4
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 57192
Gene Symbol: MCOLN1
MCOLN1
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 GeneticVariation CLINVAR

Entrez Id: 1183
Gene Symbol: CLCN4
CLCN4
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 57505
Gene Symbol: AARS2
AARS2
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 57572
Gene Symbol: DOCK6
DOCK6
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO

Entrez Id: 196528
Gene Symbol: ARID2
ARID2
CUI: C0023529
Disease: Leukomalacia, Periventricular
Leukomalacia, Periventricular
0.100 Biomarker HPO