×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Preoperative Panel Testing for Hereditary Cancer Syndromes Does Not Significantly Impact Time to Surgery for Newly Diagnosed Breast Cancer Patients Compared with BRCA1 /2 Testing.
28766202 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
We conclude that GC should be considered as a part of BRCA1 -related hereditary cancer syndrome .
23532817 2013
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Here we tested the performance of the Ion Torrent PGM platform with the Ion AmpliSeq BRCA1 and BRCA2 Panel in our clinical routine of breast/ovarian hereditary cancer syndrome assessment.
31065452 2019
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Lynch syndrome and BRCA-1 and BRCA-2-associated hereditary breast and ovarian cancer are hereditary cancer syndromes frequently involving the gynaecological tract but tumours associated with similar molecular alterations may also occur sporadically.
29287922 2018
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
Biomarker
BEFREE
Occurrence of childhood tumors in hereditary cancer syndromes such as BRCA1 /2 associated breast and ovarian cancer, DNA-mismatch repair (MMR) genes associated hereditary non polyposis colorectal cancer and CDKN2A associated familial malignant melanoma are very little studied.
18481196 2008
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutations in ovarian cancer patients from China: ethnic-related mutations in BRCA1 associated with an increased risk of ovarian cancer.
28176296 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
"A new case of ""de novo"" BRCA1 mutation in a patient with early-onset breast cancer."
28265380 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A case series of three Sri Lankan families with hereditary breast and ovarian cancer syndrome due to pathogenic germline mutations in the BRCA1 gene
28390335 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Clinical Variant Classification: A Comparison of Public Databases and a Commercial Testing Laboratory.
28408614 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex.
12732733 2003
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study.
28324225 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Primary ovarian dysgerminoma in a patient with a germline BRCA1 mutation.
11109172 2000
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
BRCA1 and BRCA2 mutations in breast cancer patients from Venezuela.
23096355 2012
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Mutations in the BRCT domain confer temperature sensitivity to BRCA1 in transcription activation.
12496477 2003
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Comparison of locus-specific databases for BRCA1 and BRCA2 variants reveals disparity in variant classification within and among databases.
25782689 2015
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
The prevalence and spectrum of BRCA1 and BRCA2 mutations in Korean population: recent update of the Korean Hereditary Breast Cancer (KOHBRA) study.
25863477 2015
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Large regional differences in the frequency of distinct BRCA1/BRCA2 mutations in 517 Dutch breast and/or ovarian cancer families.
11597388 2001
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
GeneticVariation
CLINVAR
Pathologic characteristics of breast parenchyma in patients with hereditary breast carcinoma, including BRCA1 and BRCA2 mutation carriers.
12491499 2003
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Ten novel BRCA1 and BRCA2 mutations in breast and/or ovarian cancer families from northern Germany.
11102986 2000
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
A specific GFP expression assay, penetrance estimate, and histological assessment for a putative splice site mutation in BRCA1.
12815598 2003
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan.
12181777 2002
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Spectrum of genetic variants of BRCA1 and BRCA2 in a German single center study.
28324225 2017
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Breast and ovarian cancer risks in a large series of clinically ascertained families with a high proportion of BRCA1 and BRCA2 Dutch founder mutations.
24285858 2014
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Genetic characterization of early onset ovarian carcinoma.
26718727 2016
×
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
Neoplastic Syndromes, Hereditary
0.150
CausalMutation
CLINVAR
Germline mutations of BRCA1 and BRCA2 genes in Turkish breast, ovarian, and prostate cancer patients.
21156238 2010