Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 55486
Gene Symbol: PARL
PARL
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Thus, our findings reveal that the PHB2-PARL-PGAM5-PINK1 axis is a novel pathway of PHB2-mediated mitophagy and that targeting PHB2 with the chemical compound FL3 is a promising strategy for cancer therapy. 31177901

2020

Entrez Id: 100885798
Gene Symbol: LINC00210
LINC00210
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Linc00210 enhances the malignancy of thyroid cancer cells by modulating miR-195-5p/IGF1R/Akt axis. 31240707

2020

Entrez Id: 2828
Gene Symbol: GPR4
GPR4
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The expression level of BRAF positively correlates with that of DBT in all cancer types and with that of GPR4 in most cancer types. 31548614

2020

Entrez Id: 261729
Gene Symbol: STEAP2
STEAP2
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE The six-transmembrane epithelial antigen of prostate 2 (STEAP2) protein was identified in advanced prostate cancer, and is highly over-expressed in various types of cancer. 31696760

2020

Entrez Id: 51652
Gene Symbol: CHMP3
CHMP3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE TImer algorithm was used to provide an overview of the expression of CHMP3 gene across human pan-cancer, to predict the survival outcome of breast cancer patients, and to predict the correlation between CHMP3 gene expression and epithelial-mesenchymal transition (EMT) and mitogen-activated protein kinase (MAPK)-related gene expression. 31541468

2020

Entrez Id: 1610
Gene Symbol: DAO
DAO
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The flavoenzyme D-amino acid oxidase (DAAO) represents a potentially good option for cancer enzyme prodrug therapy as it produces H<sub>2</sub>O<sub>2</sub> using D-amino acids as substrates, compounds present at low concentration in vivo and that can be safely administered to regulate H<sub>2</sub>O<sub>2</sub> production. 31706037

2020

Entrez Id: 100131814
Gene Symbol: LINC00271
LINC00271
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE Adrenocortical tumors have a distinct, long, non-coding RNA expression profile and LINC00271 is downregulated in malignancy. 31522749

2020

Entrez Id: 9993
Gene Symbol: DGCR2
DGCR2
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The risk to benefit ratio of IDD makes it a relatively safe therapy for both cancer- and noncancer-related pain, but it is not free of risks, so it should be managed at specific centers. 31435916

2020

Entrez Id: 56651
Gene Symbol: LINC00470
LINC00470
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Recently, long noncoding RNA (lncRNA) LINC00470 has been demonstrated to play an oncogenic role in human cancer. 31711642

2020

Entrez Id: 100126296
Gene Symbol: MIR298
MIR298
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 AlteredExpression BEFREE Collectively, these data showed that abnormal level of miR-298 correlated with cancer development and through that lowered the overall survival rate of CRC patients. 31621072

2020

Entrez Id: 693146
Gene Symbol: MIR561
MIR561
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE MiR-561 has been reported to be downregulated in gastric cancer and affects cancer cell proliferation and metastasis. 31711559

2020

Entrez Id: 26031
Gene Symbol: OSBPL3
OSBPL3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. 31659255

2020

Entrez Id: 55850
Gene Symbol: USE1
USE1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE These results suggest that USE1 BRCs may have future clinical applications as an RNAi-based cancer therapy. 31791842

2020

Entrez Id: 4879
Gene Symbol: NPPB
NPPB
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Scientific databases were searched for studies that assessed troponins or BNP/NT-proBNP in adult patients undergoing cancer therapy. 31721381

2020

Entrez Id: 100233209
Gene Symbol: PCED1B-AS1
PCED1B-AS1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE To unveil a novel lncRNA functioning in glioma, we browsed the cancer genome atlas dataset and chose the lncRNA PC-esterase domain containing 1B antisense RNA 1 (PCED1B-AS1) for further investigations. 31680313

2020

Entrez Id: 1741
Gene Symbol: DLG3
DLG3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE SAP102 contributes to hyperalgesia formation in the cancer induced bone pain rat model by anchoring NMDA receptors. 31682872

2020

Entrez Id: 1299
Gene Symbol: COL9A3
COL9A3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE The risk to benefit ratio of IDD makes it a relatively safe therapy for both cancer- and noncancer-related pain, but it is not free of risks, so it should be managed at specific centers. 31435916

2020

Entrez Id: 246319
Gene Symbol: VAMAS6
VAMAS6
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Occurrences and Outcomes of Immune Checkpoint Inhibitors-Induced Vitiligo in Cancer Patients: A Retrospective Cohort Study. 31630381

2020

Entrez Id: 100874365
Gene Symbol: HOXC-AS3
HOXC-AS3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In this work, the role of HOXC-AS3 in breast cancer progression was investigated.<b>Methods:</b> By using Cancer Genome Atlas (TCGA) Database, we investigated the expression of HOXC-AS3 in breast cancer and explored the association between HOXC-AS3 expression and prognosis. 31797701

2020

Entrez Id: 440503
Gene Symbol: PLIN5
PLIN5
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 GeneticVariation BEFREE Superoxide generation rate, activity of complex I in electron transport chain of mitochondria, activity of matrix metalloproteinase (MMP-2 and 9) of adipose tissues (AT) of patients with gastric cancer in AT located adjacent to tumor (ATAT) and at a distance of 3 cm (ATD) are measured to follow the connection of the redox state with some of the microenvironment indicators (HIF-1α, CD68, Plin5), body mass index (BMI) and cancer metastasis. 31711773

2020

Entrez Id: 11328
Gene Symbol: FKBP9
FKBP9
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE FKBP9 may be a cancer promoter that enhances PCa progression, and the level of FKBP9 may be used as an independent precursor of PCa patients. 31780055

2020

Entrez Id: 115253422
Gene Symbol: DUS4L-BCAP29
DUS4L-BCAP29
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In summary, we believe that in contrast to traditional gene fusions, DUS4L-BCAP29 cannot be used as a cancer biomarker. 31728976

2020

Entrez Id: 9918
Gene Symbol: NCAPD2
NCAPD2
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE For the first time, we report the close association between NCAPD2 and cancer and demonstrate that NCAPD2 plays an important role in TNBC progression and acts as an independent poor prognostic factor and a potential therapeutic target for TNBC. 31610177

2020

Entrez Id: 80853
Gene Symbol: KDM7A
KDM7A
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE In conclusion, KDM7A promotes cancer stem cell maintenance and apoptosis inhibition in breast cancer. 31236965

2020

Entrez Id: 57152
Gene Symbol: SLURP1
SLURP1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Recently, a number of myositis-specific and -associated autoantibodies (MSAs/MAAs) have been identified and well characterized, and commercial assays for their detection have become available.<b>Areas covered</b>: There is accumulating evidence showing the utility of MSAs/MAAs in diagnosis of DM and in predicting clinical courses and outcomes in patients with DM as convenient biomarkers, i.e. an association of ILD with anti-ARS, anti-MDA5 and anti-SAE; and malignancy with anti-TIF1-γ, anti-NXP2, and anti-SAE in adults. 31779485

2020