DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Longevity ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	10257
Gene Symbol:	ABCC4

ABCC4

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	10257
Gene Symbol:	ABCC4

ABCC4

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	283383
Gene Symbol:	ADGRD1

ADGRD1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	283383
Gene Symbol:	ADGRD1

ADGRD1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	441282
Gene Symbol:	AKR1B15

AKR1B15

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	441282
Gene Symbol:	AKR1B15

AKR1B15

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	8644
Gene Symbol:	AKR1C3

AKR1C3

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Novel loci and pathways significantly associated with longevity.

26912274

2016

Entrez Id:	284232
Gene Symbol:	ANKRD20A9P

ANKRD20A9P

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Novel loci and pathways significantly associated with longevity.

26912274

2016

Entrez Id:	348
Gene Symbol:	APOE

APOE

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

31413261

2019

Entrez Id:	84310
Gene Symbol:	C7orf50

C7orf50

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	84310
Gene Symbol:	C7orf50

C7orf50

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	253559
Gene Symbol:	CADM2

CADM2

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.

25199915

2015

Entrez Id:	833
Gene Symbol:	CARS1

CARS1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	833
Gene Symbol:	CARS1

CARS1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	1002
Gene Symbol:	CDH4

CDH4

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	1002
Gene Symbol:	CDH4

CDH4

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	100048912
Gene Symbol:	CDKN2B-AS1

CDKN2B-AS1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

31413261

2019

Entrez Id:	84902
Gene Symbol:	CEP89

CEP89

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

31413261

2019

Entrez Id:	1289
Gene Symbol:	COL5A1

COL5A1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	1289
Gene Symbol:	COL5A1

COL5A1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	202
Gene Symbol:	CRYBG1

CRYBG1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASDB

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	202
Gene Symbol:	CRYBG1

CRYBG1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Joint influence of small-effect genetic variants on human longevity.

20834067

2010

Entrez Id:	1595
Gene Symbol:	CYP51A1

CYP51A1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.

25918517

2015

Entrez Id:	1892
Gene Symbol:	ECHS1

ECHS1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.

25918517

2015

Entrez Id:	2138
Gene Symbol:	EYA1

EYA1

CUI:	C0023980
Disease:	Longevity

Longevity

0.100

GeneticVariation

GWASCAT

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

24688116

2014