Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations. 24243757

2013
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Pathogenic LRRK2 variants are gain-of-function mutations that enhance LRRK2-mediated repression of β-catenin signaling. 28103901

2017
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Clinical traits of LRRK2-associated Parkinson's disease in Ireland: a link between familial and idiopathic PD. 16102999

2005
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Comprehensive analysis of LRRK2 in publicly available Parkinson's disease cases and neurologically normal controls. 18213618

2008
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity. 17200152

2007
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. 15541309

2004
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR Disease penetrance of late-onset parkinsonism: a meta-analysis. 25330418

2014
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2
CUI: C0026650
Disease: Movement Disorders
Movement Disorders 		0.170 CausalMutation CLINVAR LRRK2 gene in Parkinson disease: mutation analysis and case control association study. 16157901

2005