Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11261
Gene Symbol: CHP1
CHP1
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE Two distinct cell morphologies were appreciated and separated in a long-established culture line (CHP-100) of human neuroblastoma. 6825097

1983

Entrez Id: 10058
Gene Symbol: ABCB6
ABCB6
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE Antisera to bovine serum albumin (BSA) react with biosynthetic products of the LAN-1 neuroblastoma cell line. 6848198

1983

Entrez Id: 9993
Gene Symbol: DGCR2
DGCR2
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE Antisera to bovine serum albumin (BSA) react with biosynthetic products of the LAN-1 neuroblastoma cell line. 6848198

1983

Entrez Id: 171177
Gene Symbol: RHOV
RHOV
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.090 Biomarker BEFREE Two distinct cell morphologies were appreciated and separated in a long-established culture line (CHP-100) of human neuroblastoma. 6825097

1983

Entrez Id: 338386
Gene Symbol: HSR
HSR
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.010 Biomarker BEFREE A second, randomly cloned, amplified DNA segment from the HSR of one of the neuroblastoma lines is amplified in a subset of the lines in which NB-19-21 is amplified. 6197179

1983

Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE In neuroblastoma lines in which the N-myc gene is present as a single copy, the expression of N-myc as messenger RNA is increased relative to that in nonneuroblastoma cell lines and tumors. 6505694

1984

Entrez Id: 4953
Gene Symbol: ODC1
ODC1
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE A human neuroblastoma cell line with an altered ornithine decarboxylase. 6436232

1984

Entrez Id: 7432
Gene Symbol: VIP
VIP
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE The quantity of VIP/PHM-27 gene in the DNA of neuroblastoma cells was analyzed after hydrolysis with a restriction endonuclease, EcoRI. 6086627

1984

Entrez Id: 567
Gene Symbol: B2M
B2M
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.060 Biomarker BEFREE Previous work showed that each of four human neuronal cell lines expresses less than or equal to 0.5% of the HLA-A,B,C and beta 2-microglobulin seen in glial, lymphoid, and other cell types, and there is a corresponding weak expression in neuroblastoma tumor and adult brain. 6436814

1984

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 AlteredExpression BEFREE In contrast, three tumor types, teratocarcinoma, choriocarcinoma, and neuroblastoma, were not inducible for Ia expression, even though IFN-gamma could induce expression of HLA-A,B,C products. 6204001

1984

Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 AlteredExpression BEFREE Previous work showed that each of four human neuronal cell lines expresses less than or equal to 0.5% of the HLA-A,B,C and beta 2-microglobulin seen in glial, lymphoid, and other cell types, and there is a corresponding weak expression in neuroblastoma tumor and adult brain. 6436814

1984

Entrez Id: 7432
Gene Symbol: VIP
VIP
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression BEFREE Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells. 2416313

1985

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE N-myc is a DNA sequence which shares limited homology to the proto-oncogene c-myc and has been found to be amplified in both primary tissue and cell lines from neuroblastoma, a childhood tumour of neuroectodermal origin. 3855502

1985

Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE We have analyzed a 3.8 kb Eco RI fragment of genomic DNA obtained from the amplified N-myc gene of human neuroblastoma cell line BE(2)-C. This fragment contains an exon with an open reading frame encoding approximately 170 amino acids of the carboxy-terminal end of the putative N-myc protein. 2987858

1985

Entrez Id: 11261
Gene Symbol: CHP1
CHP1
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 Biomarker BEFREE Chromosomal features of CHP-382/JK shared with other neuroblastoma cell lines were the deletion of 1p and the presence of extra 17q material. 2582423

1985

Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression BEFREE The N-myc gene, first detected by its homology to the second exon of the c-myc gene, is amplified and/or expressed in tumours or cell lines derived from neuroblastoma, retinoblastoma and SCLC. 2997622

1985

Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression BEFREE The N-myc gene, first detected by its homology to the second exon of the c-myc gene, is amplified and/or expressed in tumours or cell lines derived from neuroblastoma, retinoblastoma and SCLC. 2997622

1985

Entrez Id: 353
Gene Symbol: APRT
APRT
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.090 AlteredExpression BEFREE Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells. 2416313

1985

Entrez Id: 4236
Gene Symbol: MFAP1
MFAP1
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.090 AlteredExpression BEFREE Synergistic stimulation of VIP/PHM-27 gene expression by cyclic AMP and phorbol esters in human neuroblastoma cells. 2416313

1985

Entrez Id: 171177
Gene Symbol: RHOV
RHOV
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.090 Biomarker BEFREE Chromosomal features of CHP-382/JK shared with other neuroblastoma cell lines were the deletion of 1p and the presence of extra 17q material. 2582423

1985

Entrez Id: 2051
Gene Symbol: EPHB6
EPHB6
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.070 Biomarker BEFREE Persistent infection of rabies virus (HEP-Flury strain) in human neuroblastoma cells capable of producing interferon. 3998711

1985

Entrez Id: 7070
Gene Symbol: THY1
THY1
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 AlteredExpression BEFREE K117, the putative human Thy-1 antigen, was expressed at high levels in chromosome 11-containing hybrids constructed with mouse neuroblastoma cells, but showed little or no expression in hybrids constructed with mouse L cells. 2865325

1985

Entrez Id: 10855
Gene Symbol: HPSE
HPSE
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.030 Biomarker BEFREE Persistent infection of rabies virus (HEP-Flury strain) in human neuroblastoma cells capable of producing interferon. 3998711

1985

Entrez Id: 728489
Gene Symbol: DNLZ
DNLZ
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.020 Biomarker BEFREE Persistent infection of rabies virus (HEP-Flury strain) in human neuroblastoma cells capable of producing interferon. 3998711

1985

Entrez Id: 4613
Gene Symbol: MYCN
MYCN
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
0.100 AlteredExpression BEFREE We have demonstrated that the entire murine N-myc gene and the sequences necessary for its expression in human neuroblastoma cells are contained within a 7.4-kilobase murine genomic clone. 3513190

1986